A meta-analysis of robotic vs. conventional mitral valve surgery

Christopher Cao, Hugh Wolfenden, Kevin Liou, Faraz Pathan, Sunil Gupta, Thomas A. Nienaber, David Chandrakumar, Praveen Indraratna, Tristan D. Yan

Research output: Contribution to journalArticlepeer-review


Objectives: The present study is the first meta-analysis to compare the surgical outcomes of robotic vs. conventional mitral valve surgery in patients with degenerative mitral valve disease. 

Methods: A systematic review of the literature was conducted to identify all relevant studies with comparative data on robotic vs. conventional mitral valve surgery. Predefined primary endpoints included mortality, stroke and reoperation for bleeding. Secondary endpoints included cross-clamp time, cardiopulmonary bypass time, length of hospitalization and duration of intensive care unit (ICU) stay. Echocardiographic outcomes were assessed when possible. 

Results: Six relevant retrospective studies with comparative data for robotic vs. conventional mitral valve surgery were identified from the existing literature. Meta-analysis demonstrated a superior perioperative survival outcome for patients who underwent robotic surgery. Incidences of stroke and reoperation were not statistically different between the two treatment arms. Patients who underwent robotic surgery required a significantly longer period of cardiopulmonary bypass time and cross-clamp time. However, the lengths of hospitalization and ICU stay were not significantly different. Both surgical techniques appeared to achieve satisfactory echocardiographic outcomes in the majority of patients. 

Conclusions: Current evidence on comparative outcomes of robotic vs. conventional mitral surgery is limited, and results of the present meta-analysis should be interpreted with caution due to differing patient characteristics. However, it has been demonstrated that robotic mitral valve surgery can be safely performed by expert surgeons for selected patients. A successful robotic program is dependent on a specially trained team and a sufficient volume of referrals to attain and maintain safety.

Original languageEnglish
Pages (from-to)305-314
Number of pages10
JournalAnnals of Cardiothoracic Surgery
Issue number4
Publication statusPublished - 2015


  • Mini-mitral
  • robotic surgery
  • meta-analysis
  • mitral valve


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