A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage

Michelle L. Power*, Belinda C. Ferrari, Jane Littlefield-Wyer, David M. Gordon, Martin B. Slade, Duncan A. Veal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele.

Original languageEnglish
Pages (from-to)7930-7932
Number of pages3
JournalApplied and Environmental Microbiology
Volume72
Issue number12
DOIs
Publication statusPublished - Dec 2006

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