A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage

Michelle L. Power, Belinda C. Ferrari, Jane Littlefield-Wyer, David M. Gordon, Martin B. Slade, Duncan A. Veal

Research output: Contribution to journalArticleResearchpeer-review

Abstract

A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele.

LanguageEnglish
Pages7930-7932
Number of pages3
JournalApplied and Environmental Microbiology
Volume72
Issue number12
DOIs
Publication statusPublished - Dec 2006

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outer membrane proteins
bacteriophage
bacteriophages
Bacteriophages
allele
Membrane Proteins
Alleles
Escherichia coli
membrane
alleles
Virus Receptors
protein
surface proteins
Proteomics
proteomics
genetic polymorphism
DNA
polymorphism
proteins
testing

Cite this

Power, Michelle L. ; Ferrari, Belinda C. ; Littlefield-Wyer, Jane ; Gordon, David M. ; Slade, Martin B. ; Veal, Duncan A. / A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage. In: Applied and Environmental Microbiology. 2006 ; Vol. 72, No. 12. pp. 7930-7932.
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A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage. / Power, Michelle L.; Ferrari, Belinda C.; Littlefield-Wyer, Jane; Gordon, David M.; Slade, Martin B.; Veal, Duncan A.

In: Applied and Environmental Microbiology, Vol. 72, No. 12, 12.2006, p. 7930-7932.

Research output: Contribution to journalArticleResearchpeer-review

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