Abstract
A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.
Original language | English |
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Pages (from-to) | 2436-2439 |
Number of pages | 4 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 35 |
Issue number | 11 |
Publication status | Published - 1991 |