A novel method for retinal vessel segmentation and diameter measurement using high speed video

Mahdieh Rezaeian; Mark Butlin; S. Mojtaba Golzan; Stuart L. Graham; Alberto P. Avolio

doi:10.1109/EMBC.2019.8856879

A novel method for retinal vessel segmentation and diameter measurement using high speed video

Mahdieh Rezaeian^*, Mark Butlin, S. Mojtaba Golzan, Stuart L. Graham, Alberto P. Avolio

^*Corresponding author for this work

Faculty of Medicine, Health and Human Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

2 Citations (Scopus)

Abstract

Studying dynamic characteristics of retinal vessels, as opposed to static measures, may provide additional insight into pathophysiological changes associated with local and systemic abnormalities such as glaucoma and hypertension. Various approaches have been developed to derive static biomarkers from retinal still images, but not many for dynamic analysis of video sequences. This study presents a novel method for the assessment of time-dependent diameter changes in high-speed videos (125 fps) from the rat retina. The proposed method is composed of a vessel segmentation and a diameter measurement module. The specificity and sensitivity of the segmentation method over 25 images were 95.1% and 97.3% respectively. The mean and standard deviation of the diameter measurement errors were -0.147±0.41 pixels over 100 measurements.

Original language	English
Title of host publication	2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Place of Publication	Piscataway, NJ
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	2781-2784
Number of pages	4
ISBN (Electronic)	9781538613115
ISBN (Print)	9781538613122
DOIs	https://doi.org/10.1109/EMBC.2019.8856879
Publication status	Published - 1 Jul 2019
Event	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 - Berlin, Germany Duration: 23 Jul 2019 → 27 Jul 2019

Conference

Conference	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Country/Territory	Germany
City	Berlin
Period	23/07/19 → 27/07/19

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10.1109/EMBC.2019.8856879

Cite this

Rezaeian, M., Butlin, M., Golzan, S. M., Graham, S. L., & Avolio, A. P. (2019). A novel method for retinal vessel segmentation and diameter measurement using high speed video. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 (pp. 2781-2784). Article 8856879 Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/EMBC.2019.8856879

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abstract = "Studying dynamic characteristics of retinal vessels, as opposed to static measures, may provide additional insight into pathophysiological changes associated with local and systemic abnormalities such as glaucoma and hypertension. Various approaches have been developed to derive static biomarkers from retinal still images, but not many for dynamic analysis of video sequences. This study presents a novel method for the assessment of time-dependent diameter changes in high-speed videos (125 fps) from the rat retina. The proposed method is composed of a vessel segmentation and a diameter measurement module. The specificity and sensitivity of the segmentation method over 25 images were 95.1% and 97.3% respectively. The mean and standard deviation of the diameter measurement errors were -0.147±0.41 pixels over 100 measurements.",

author = "Mahdieh Rezaeian and Mark Butlin and Golzan, {S. Mojtaba} and Graham, {Stuart L.} and Avolio, {Alberto P.}",

year = "2019",

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doi = "10.1109/EMBC.2019.8856879",

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Rezaeian, M, Butlin, M, Golzan, SM, Graham, SL & Avolio, AP 2019, A novel method for retinal vessel segmentation and diameter measurement using high speed video. in 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019., 8856879, Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, pp. 2781-2784, 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019, Berlin, Germany, 23/07/19. https://doi.org/10.1109/EMBC.2019.8856879

A novel method for retinal vessel segmentation and diameter measurement using high speed video. / Rezaeian, Mahdieh; Butlin, Mark; Golzan, S. Mojtaba et al.
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), 2019. p. 2781-2784 8856879.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

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AB - Studying dynamic characteristics of retinal vessels, as opposed to static measures, may provide additional insight into pathophysiological changes associated with local and systemic abnormalities such as glaucoma and hypertension. Various approaches have been developed to derive static biomarkers from retinal still images, but not many for dynamic analysis of video sequences. This study presents a novel method for the assessment of time-dependent diameter changes in high-speed videos (125 fps) from the rat retina. The proposed method is composed of a vessel segmentation and a diameter measurement module. The specificity and sensitivity of the segmentation method over 25 images were 95.1% and 97.3% respectively. The mean and standard deviation of the diameter measurement errors were -0.147±0.41 pixels over 100 measurements.

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Rezaeian M, Butlin M, Golzan SM, Graham SL , Avolio AP. A novel method for retinal vessel segmentation and diameter measurement using high speed video. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). 2019. p. 2781-2784. 8856879 doi: 10.1109/EMBC.2019.8856879

A novel method for retinal vessel segmentation and diameter measurement using high speed video

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