A Novel Needle-Type SV-GMR Sensor for Biomedical Applications

Subhas Chandra Mukhopadhyay, Chnithaka P. Gooneratne, Sotoshi Yamada

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


Cancer is the most deadly disease in the world today. There is a variety of different treatment methods for cancer, including radiotherapy and chemotherapy with anticancer drugs that have been in use over a long period of time. Hyperthermia is one of the cancer treatment methods that utilizes the property that cancer cells are more sensitive to temperature than normal cells. The control of temperature is an important task in achieving success using this treatment method. This paper reports the development of a novel needle-type nanosensor based on the spin-valve giant magnetoresistive (SV-GMR) technique to measure the magnetic flux density inside the body via pricking the needle. The sensor has been fabricated. The modeling and experimental results of flux density measurement have been reported. From the information of flux density, the temperature rise can be estimated to permit the delivery of controlled heating to precisely defined locations in controlled hyperthermia cancer treatment. The actual experiment with human is under investigation.

Original languageEnglish
Pages (from-to)401-408
Number of pages8
JournalIEEE Sensors Journal
Issue number3
Publication statusPublished - 7 Mar 2007
Externally publishedYes


  • Cancer
  • hyperthermia treatment
  • magnetic fluid nanosensor
  • semi-invasive
  • spin-valve giant magnetoresistive (SV-GMR) sensor


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