TY - JOUR
T1 - A perspective to the correlation between brain insulin resistance and Alzheimer
T2 - medicinal chemistry approach
AU - Rabiee, Navid
AU - Bagherzadeh, Mojtaba
AU - Rabiee, Mohammad
PY - 2019
Y1 - 2019
N2 - Substantial terms have been recognized on the associated risk elements, comorbidities as well as, putative pathophysiological processes of Alzheimer disease and related dementias (ADRDs) as well as, type 2 diabetes mellitus (T2DM), a few from greatest important disease from the moments. Very much is considered regarding the biology and chemistry of each predicament, nevertheless T2DM and ADRDs are an actually similar pattern developing from the similar origins of maturing or synergistic conditions connected by aggressive patho-corporeal terms and continues to be ambiguous. In this depth-critique article, we aimed to investigate all possibilities and represented a novel and applicable approach from the Medicinal Chemistry concepts.
AB - Substantial terms have been recognized on the associated risk elements, comorbidities as well as, putative pathophysiological processes of Alzheimer disease and related dementias (ADRDs) as well as, type 2 diabetes mellitus (T2DM), a few from greatest important disease from the moments. Very much is considered regarding the biology and chemistry of each predicament, nevertheless T2DM and ADRDs are an actually similar pattern developing from the similar origins of maturing or synergistic conditions connected by aggressive patho-corporeal terms and continues to be ambiguous. In this depth-critique article, we aimed to investigate all possibilities and represented a novel and applicable approach from the Medicinal Chemistry concepts.
KW - ADRDs
KW - Alzheimer
KW - Human post-mortem
KW - Insulin resistance
KW - Medicinal chemistry
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=85068775561&partnerID=8YFLogxK
U2 - 10.2174/1573399814666181031154817
DO - 10.2174/1573399814666181031154817
M3 - Article
C2 - 30381082
AN - SCOPUS:85068775561
VL - 15
SP - 255
EP - 258
JO - Current Diabetes Reviews
JF - Current Diabetes Reviews
SN - 1573-3998
IS - 4
ER -