A practical guide for Fractional Flow Reserve guided revascularisation

Abdul Rahman Ihdayhid, Andy Yong, Richard Harper, Jamie Rankin, Christopher Wong, Adam J. Brown, Michael Leung, Brian Ko*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


The presence and extent of myocardial ischaemia is a major determinant of prognosis and benefit from revascularisation in patients with stable coronary artery disease. Fractional Flow Reserve (FFR) is accepted as the reference standard for invasive assessment of ischaemia. Its ability to detect lesion specific ischaemia makes it a useful test in a wide range of patient and lesion subsets, with FFR guided intervention improving clinical outcomes and reducing health care costs compared to assessment with coronary angiography alone. This article will review the basic principles in FFR, practical tips in FFR guided revascularisation and the role of emerging non-hyperaemic indices of ischaemia.

Original languageEnglish
Pages (from-to)406-419
Number of pages14
JournalHeart, Lung and Circulation
Issue number4
Publication statusPublished - 1 Apr 2018
Externally publishedYes


  • Coronary artery disease
  • Fractional flow reserve
  • Functional assessment
  • Percutaneous coronary intervention


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