A Preliminary study of vascular morphological changes and their numerical simulation of fluid dynamics after anterior communicating artery aneurysms treated with stents

Yong-fa Wu, Qing-hai Huang, Sheng-zhang Wang, Peng-fei Yang, Yi Qian, Jian-min Liu

    Research output: Contribution to journalArticle

    Abstract

    Objective: To investigate the outcome of wide-necked anterior communicating artery aneurysm treated with stent placement. Methods: One patient with wide-necked anterior communicating artery aneurysm was treated with stent-assisted coil embolization. The three-dimensional blood vessels model was reconstructed by the software of computational fluid dynamics (CFD) finite element method. Before stent placement, the aneurysm was resected and the corresponding vessel wall at the aneurysm neck was repaired to simulate and the results of dense embolization by coils. The changes of vascular morphology before and after the stent placement were compared. The hemodynamic parameters under the different vascular morphologies were analyzed, induding blood flow line, pressure, and wall shear stress (WSS) and so on. Results (l)The vascular morphology changed obviously after stent placement as compared to the dense packing with the simple coils. The vessel angles of ipsilateral anterior cerebral artery Al and A2 segments increased 14.4 degrees. (2) After stent placement, the blood eddy current reduced significanlly at the corresponding vascular segment of the aneurysm neck, and the blood flow line tended to be straight. (3)After dense packing with the simple coils, the mean WSS al the aneurysm neck was 11.55Pa; after stent placement, the mean WSS of the blood vessel wall was 7.93Pa (decreased 31.3%). Conclusion: The wide-necked anterior communicating artery aneurysm treated with stent placement may significantly change the vascular morphology of parent artery and change the local hemodynamics of parent artery, and reduce the WSS of aneurysm.
    Original languageChinese
    Pages (from-to)148-151
    Number of pages4
    JournalChinese Journal of Cerebrovascular Diseases
    Volume8
    Issue number3
    Publication statusPublished - 2011

    Keywords

    • intracranial aneurysm
    • stent
    • computer simulation
    • morphology

    Cite this