A Protein annotation framework empowered with semantic reasoning

Jemma X. Wu; Edmond J. Breen; Xiaomin Song; Brett Cooke; Mark P. Molloy

A Protein annotation framework empowered with semantic reasoning

Jemma X. Wu, Edmond J. Breen, Xiaomin Song, Brett Cooke, Mark P. Molloy

Australian Proteome Analysis Facility (APAF)

Research output: Contribution to journal › Article › peer-review

Abstract

This paper presents an association discovery framework for proteins based on semantic annotations from biomedical literatures. An automatic ontology-based annotation method is used to create a semantic protein annotation knowledge base. A semantic reasoning service enables realisation reasoning on original annotations to infer more accurate associations. A case study on protein-disease association discovery on a real-world colorectal cancer dataset is presented.

Original language	English
Pages (from-to)	185-188
Number of pages	4
Journal	CEUR Workshop Proceedings
Volume	1035
Publication status	Published - 2013

Keywords

bioinformatics
protein annotation
semantic reasoning

Cite this

@article{4923cfd480dc44f398c7e9f2dfe210f5,

title = "A Protein annotation framework empowered with semantic reasoning",

abstract = "This paper presents an association discovery framework for proteins based on semantic annotations from biomedical literatures. An automatic ontology-based annotation method is used to create a semantic protein annotation knowledge base. A semantic reasoning service enables realisation reasoning on original annotations to infer more accurate associations. A case study on protein-disease association discovery on a real-world colorectal cancer dataset is presented.",

keywords = "bioinformatics, protein annotation, semantic reasoning",

author = "Wu, {Jemma X.} and Breen, {Edmond J.} and Xiaomin Song and Brett Cooke and Molloy, {Mark P.}",

year = "2013",

language = "English",

volume = "1035",

pages = "185--188",

journal = "CEUR Workshop Proceedings",

issn = "1613-0073",

publisher = "RWTH Aachen University",

}

TY - JOUR

T1 - A Protein annotation framework empowered with semantic reasoning

AU - Wu, Jemma X.

AU - Breen, Edmond J.

AU - Song, Xiaomin

AU - Cooke, Brett

AU - Molloy, Mark P.

PY - 2013

Y1 - 2013

N2 - This paper presents an association discovery framework for proteins based on semantic annotations from biomedical literatures. An automatic ontology-based annotation method is used to create a semantic protein annotation knowledge base. A semantic reasoning service enables realisation reasoning on original annotations to infer more accurate associations. A case study on protein-disease association discovery on a real-world colorectal cancer dataset is presented.

AB - This paper presents an association discovery framework for proteins based on semantic annotations from biomedical literatures. An automatic ontology-based annotation method is used to create a semantic protein annotation knowledge base. A semantic reasoning service enables realisation reasoning on original annotations to infer more accurate associations. A case study on protein-disease association discovery on a real-world colorectal cancer dataset is presented.

KW - bioinformatics

KW - protein annotation

KW - semantic reasoning

UR - http://www.scopus.com/inward/record.url?scp=84924657843&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84924657843

SN - 1613-0073

VL - 1035

SP - 185

EP - 188

JO - CEUR Workshop Proceedings

JF - CEUR Workshop Proceedings

ER -

A Protein annotation framework empowered with semantic reasoning

Abstract

Keywords

Other files and links

Fingerprint

Cite this