A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau

Zhiping Han; Edward S. X. Moh; Yuanhuai Peng; Sheng Wang; Bei Jin; Ying Huang; Jianzhi Ye

doi:10.1016/j.algal.2022.102767

A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau

Zhiping Han^*, Edward S. X. Moh, Yuanhuai Peng, Sheng Wang, Bei Jin, Ying Huang, Jianzhi Ye^*

^*Corresponding author for this work

School of Natural Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A new green microalga was isolated from a salt lake in Tibet Plateau, China, classified as genus Desmodesmus under the family of Scenedesmaceae based on morphological and 18S rDNA sequencing. The species was able to grow at both 4 and 25 °C, due to differences to the biochemical composition. At 25 °C, protein content made up 50 % in dry biomass, while at 4 °C lipids made up 55 % of dry biomass. A poly unsaturated fatty acid, cis-8,11,14-docosatrienoic acid (C22:3, 8,11,14-DTA), was identified in D. sp. QL96 cultured under both temperature conditions. This fatty acid has been reported to be physiologically functional, however yield from natural sources was low and limited the related research and application. GC analysis indicated that 8,11,14-DTA was the third abundant fatty acid in D. sp. QL96, accounting for around 20 % out of the total lipid. The effects of environmental factors on the production of 8,11,14-DTA was studied and productivity of 8,11,14-DTA was optimized to achieve 10.91 mg/L per day. To our knowledge, the plateau alga is the most productive natural source of 8,11,14-DTA. This study provides the groundwork for further study and processing of this fatty acid.

Original language	English
Article number	102767
Pages (from-to)	1-9
Number of pages	9
Journal	Algal Research
Volume	66
Early online date	25 Jul 2022
DOIs	https://doi.org/10.1016/j.algal.2022.102767
Publication status	Published - Jul 2022

Keywords

Desmodesmus
Plateau microalgae
Salt lake
cis-8,4,11-docosatrienoic acid

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10.1016/j.algal.2022.102767

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@article{60664c643c7343fa8ce02d85e2b731f6,

title = "A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau",

abstract = "A new green microalga was isolated from a salt lake in Tibet Plateau, China, classified as genus Desmodesmus under the family of Scenedesmaceae based on morphological and 18S rDNA sequencing. The species was able to grow at both 4 and 25 °C, due to differences to the biochemical composition. At 25 °C, protein content made up 50 \% in dry biomass, while at 4 °C lipids made up 55 \% of dry biomass. A poly unsaturated fatty acid, cis-8,11,14-docosatrienoic acid (C22:3, 8,11,14-DTA), was identified in D. sp. QL96 cultured under both temperature conditions. This fatty acid has been reported to be physiologically functional, however yield from natural sources was low and limited the related research and application. GC analysis indicated that 8,11,14-DTA was the third abundant fatty acid in D. sp. QL96, accounting for around 20 \% out of the total lipid. The effects of environmental factors on the production of 8,11,14-DTA was studied and productivity of 8,11,14-DTA was optimized to achieve 10.91 mg/L per day. To our knowledge, the plateau alga is the most productive natural source of 8,11,14-DTA. This study provides the groundwork for further study and processing of this fatty acid.",

keywords = "Desmodesmus, Plateau microalgae, Salt lake, cis-8,4,11-docosatrienoic acid",

author = "Zhiping Han and Moh, \{Edward S. X.\} and Yuanhuai Peng and Sheng Wang and Bei Jin and Ying Huang and Jianzhi Ye",

year = "2022",

month = jul,

doi = "10.1016/j.algal.2022.102767",

language = "English",

volume = "66",

pages = "1--9",

journal = "Algal Research",

issn = "2211-9264",

publisher = "Elsevier",

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T1 - A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau

AU - Han, Zhiping

AU - Moh, Edward S. X.

AU - Peng, Yuanhuai

AU - Wang, Sheng

AU - Jin, Bei

AU - Huang, Ying

AU - Ye, Jianzhi

PY - 2022/7

Y1 - 2022/7

N2 - A new green microalga was isolated from a salt lake in Tibet Plateau, China, classified as genus Desmodesmus under the family of Scenedesmaceae based on morphological and 18S rDNA sequencing. The species was able to grow at both 4 and 25 °C, due to differences to the biochemical composition. At 25 °C, protein content made up 50 % in dry biomass, while at 4 °C lipids made up 55 % of dry biomass. A poly unsaturated fatty acid, cis-8,11,14-docosatrienoic acid (C22:3, 8,11,14-DTA), was identified in D. sp. QL96 cultured under both temperature conditions. This fatty acid has been reported to be physiologically functional, however yield from natural sources was low and limited the related research and application. GC analysis indicated that 8,11,14-DTA was the third abundant fatty acid in D. sp. QL96, accounting for around 20 % out of the total lipid. The effects of environmental factors on the production of 8,11,14-DTA was studied and productivity of 8,11,14-DTA was optimized to achieve 10.91 mg/L per day. To our knowledge, the plateau alga is the most productive natural source of 8,11,14-DTA. This study provides the groundwork for further study and processing of this fatty acid.

AB - A new green microalga was isolated from a salt lake in Tibet Plateau, China, classified as genus Desmodesmus under the family of Scenedesmaceae based on morphological and 18S rDNA sequencing. The species was able to grow at both 4 and 25 °C, due to differences to the biochemical composition. At 25 °C, protein content made up 50 % in dry biomass, while at 4 °C lipids made up 55 % of dry biomass. A poly unsaturated fatty acid, cis-8,11,14-docosatrienoic acid (C22:3, 8,11,14-DTA), was identified in D. sp. QL96 cultured under both temperature conditions. This fatty acid has been reported to be physiologically functional, however yield from natural sources was low and limited the related research and application. GC analysis indicated that 8,11,14-DTA was the third abundant fatty acid in D. sp. QL96, accounting for around 20 % out of the total lipid. The effects of environmental factors on the production of 8,11,14-DTA was studied and productivity of 8,11,14-DTA was optimized to achieve 10.91 mg/L per day. To our knowledge, the plateau alga is the most productive natural source of 8,11,14-DTA. This study provides the groundwork for further study and processing of this fatty acid.

KW - Desmodesmus

KW - Plateau microalgae

KW - Salt lake

KW - cis-8,4,11-docosatrienoic acid

UR - http://purl.org/au-research/grants/arc/CE200100029

UR - https://www.scopus.com/pages/publications/85134850101

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DO - 10.1016/j.algal.2022.102767

M3 - Article

SN - 2211-9264

VL - 66

SP - 1

EP - 9

JO - Algal Research

JF - Algal Research

M1 - 102767

ER -

A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau

Abstract

Keywords

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COESB: ARC Centre of Excellence in Synthetic Biology

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A rare ω-8 fatty acid, cis-8,4,11-docosatrienoic acid rich microalgal strain isolated from a salt lake in Tibet Plateau

Abstract

Keywords

Access to Document

Other files and links

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Projects

COESB: ARC Centre of Excellence in Synthetic Biology

Cite this