A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F

D. Saul; D. Lane; P. L. Bergquist

doi:10.1111/j.1365-2958.1988.tb00023.x

A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F

D. Saul, D. Lane, P. L. Bergquist^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

A region of the IncHl plasmid R27 has been found to share very close nucleotide sequence homology with the RepFIA replicon of F. This region has been located on a 1.6 kb segment of R27 plasmid DNA, and corresponds to ori‐2 and the E gene of F. The IncC repeat sequence region shows reduced homology, with the F repeats being an imperfect subset of a larger repeated sequence found in R27. The E gene homologue of R27 is able to initiate replication from the F ori‐2 sequence and to repress the E gene promoter of F. The results are consistent with the observed incompatibility behaviour of R27, and have a bearing on the specificity of interaction of E protein with its DNA‐binding sites.

Original language	English
Pages (from-to)	219-225
Number of pages	7
Journal	Molecular Microbiology
Volume	2
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2958.1988.tb00023.x
Publication status	Published - 1988
Externally published	Yes

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10.1111/j.1365-2958.1988.tb00023.x

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title = "A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F",

abstract = "A region of the IncHl plasmid R27 has been found to share very close nucleotide sequence homology with the RepFIA replicon of F. This region has been located on a 1.6 kb segment of R27 plasmid DNA, and corresponds to ori‐2 and the E gene of F. The IncC repeat sequence region shows reduced homology, with the F repeats being an imperfect subset of a larger repeated sequence found in R27. The E gene homologue of R27 is able to initiate replication from the F ori‐2 sequence and to repress the E gene promoter of F. The results are consistent with the observed incompatibility behaviour of R27, and have a bearing on the specificity of interaction of E protein with its DNA‐binding sites.",

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doi = "10.1111/j.1365-2958.1988.tb00023.x",

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T1 - A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F

AU - Saul, D.

AU - Lane, D.

AU - Bergquist, P. L.

PY - 1988

Y1 - 1988

N2 - A region of the IncHl plasmid R27 has been found to share very close nucleotide sequence homology with the RepFIA replicon of F. This region has been located on a 1.6 kb segment of R27 plasmid DNA, and corresponds to ori‐2 and the E gene of F. The IncC repeat sequence region shows reduced homology, with the F repeats being an imperfect subset of a larger repeated sequence found in R27. The E gene homologue of R27 is able to initiate replication from the F ori‐2 sequence and to repress the E gene promoter of F. The results are consistent with the observed incompatibility behaviour of R27, and have a bearing on the specificity of interaction of E protein with its DNA‐binding sites.

AB - A region of the IncHl plasmid R27 has been found to share very close nucleotide sequence homology with the RepFIA replicon of F. This region has been located on a 1.6 kb segment of R27 plasmid DNA, and corresponds to ori‐2 and the E gene of F. The IncC repeat sequence region shows reduced homology, with the F repeats being an imperfect subset of a larger repeated sequence found in R27. The E gene homologue of R27 is able to initiate replication from the F ori‐2 sequence and to repress the E gene promoter of F. The results are consistent with the observed incompatibility behaviour of R27, and have a bearing on the specificity of interaction of E protein with its DNA‐binding sites.

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DO - 10.1111/j.1365-2958.1988.tb00023.x

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VL - 2

SP - 219

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JO - Molecular Microbiology

JF - Molecular Microbiology

SN - 0950-382X

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ER -

A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F

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