@inproceedings{f0acdc6fa84e436fabf7a4713a57604e,
title = "A reproduction of inflow restriction in the mock circulatory system to evaluate a hydrodynamic performance of a ventricular assist device in practical conditions",
abstract = "A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulating blood volume pooling due to heart failure, was developed to evaluate a hydrodynamic performance of a pulsatile ventricular assist device (VAD) in practical conditions. The concept of this development was motivated by a difference of an inflow restriction between in vitro and in vivo environments. The major idea of this study is to reproduce an inflow restriction by using a centrifugal pump placed at an inflow side of a left ventricular model instead of a constant head reservoir in a conventional circuit. In the novel circuit, the maximum flow rate was obtained at lower systolic fraction as compared with a conventional circuit. This similar tendency by the novel one was observed in an acute animal experiment in sheep. This result suggests that a new mock circuit is effective to confirm a practical drive strategy of the VAD for various diseased conditions.",
author = "Masateru Furusato and Tomohiro Shima and Yuma Kokuzawa and Kazuhiko Ito and Takashi Tanaka and Kiyotaka Iwasaki and Yi Qian and Mitsuo Umezu and Yan, {Zhi Kun} and Ling Zhu",
year = "2007",
language = "English",
isbn = "9783540747703",
volume = "4689 LNBI",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer, Springer Nature",
pages = "553--558",
editor = "Kang Li and Xin Li and Irwin, {George William} and Gusen He",
booktitle = "Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings",
address = "United States",
note = "2007 International Conference on Life System Modeling and Simulation, LSMS 2007 ; Conference date: 14-09-2007 Through 17-09-2007",
}