A review of capillary pressure control valves in microfluidics

Shaoxi Wang, Xiafeng Zhang, Cong Ma, Sheng Yan, David Inglis, Shilun Feng*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

23 Citations (Scopus)
414 Downloads (Pure)

Abstract

Microfluidics offer microenvironments for reagent delivery, handling, mixing, reaction, and detection, but often demand the affiliated equipment for liquid control for these functions. As a helpful tool, the capillary pressure control valve (CPCV) has become popular to avoid using affiliated equipment. Liquid can be handled in a controlled manner by using the bubble pressure effects. In this paper, we analyze and categorize the CPCVs via three determining parameters: surface tension, contact angle, and microchannel shape. Finally, a few application scenarios and impacts of CPCV are listed, which includes how CPVC simplify automation of microfluidic networks, work with other driving modes; make extensive use of microfluidics by open channel, and sampling and delivery with controlled manners. The authors hope this review will help the development and use of the CPCV in microfluidic fields in both research and industry.

Original languageEnglish
Article number405
Pages (from-to)1-26
Number of pages26
JournalBiosensors
Volume11
Issue number10
DOIs
Publication statusPublished - Oct 2021

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • capillary pressure control valve (CPCV0
  • microfluidics
  • passive valve

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