A second Australian family with hemoglobin north shore (β134 val→glu)

Howard Gurney, Ibrahim Baig, Susan Gordon*, Kiran Phadke, Heather Kearsley, Pat Fleming, Ken Wyatt, Wilbur Hughes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


A second Australian family is reported with Hemoglobin North Shore (β134 Val→Glu), an unstable hemoglobin, causing no clinical symptoms. All affected family members showed only mild reticulocytosis and microcytosis on the blood film, despite the strongly positive isopropanol test for Hb (hemoglobin) stability and numerous red cell inclusions. Hb North Shore constituted 31-38% of the total hemoglobin and migrated on the anodal side of Hb A at pH 8.9. The association of a mildly raised Hb A2 level and thalassemic phenotype with Hb North Shore previously reported, is confirmed in this study.

Original languageEnglish
Pages (from-to)62-63
Number of pages2
Issue number1
Publication statusPublished - 1987
Externally publishedYes


  • Raised Hb A2
  • Red cell inclusions
  • Unstable hemoglobin


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