A method for perfusion fixation of the sheep central nervous system is described. The technique utilises the vascular anatomy of the spinal cord and brain to provide fixation that is comparable to transcardiac perfusion of the small animal. It can be applied with relative ease, cost effectiveness and without risking premature death of the animal due to complications of a major procedure such as thoracotomy.
|Number of pages||5|
|Journal||Journal of Neuroscience Methods|
|Publication status||Published - 20 Feb 1998|
- Perfusion fixation
- Tissue fixation
- Tissue preservation