A technique for in vivo vascular perfusion fixation of the sheep central nervous system

Stephen Santoreneos; Marcus A. Stoodley; Nigel R. Jones; Chris J. Brown

doi:10.1016/S0165-0270(97)00180-5

A technique for in vivo vascular perfusion fixation of the sheep central nervous system

Stephen Santoreneos^*, Marcus A. Stoodley, Nigel R. Jones, Chris J. Brown

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A method for perfusion fixation of the sheep central nervous system is described. The technique utilises the vascular anatomy of the spinal cord and brain to provide fixation that is comparable to transcardiac perfusion of the small animal. It can be applied with relative ease, cost effectiveness and without risking premature death of the animal due to complications of a major procedure such as thoracotomy.

Original language	English
Pages (from-to)	195-199
Number of pages	5
Journal	Journal of Neuroscience Methods
Volume	79
Issue number	2
DOIs	https://doi.org/10.1016/S0165-0270(97)00180-5
Publication status	Published - 20 Feb 1998
Externally published	Yes

Keywords

Fixatives
Methods
Perfusion fixation
Tissue fixation
Tissue preservation

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10.1016/S0165-0270(97)00180-5

Cite this

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abstract = "A method for perfusion fixation of the sheep central nervous system is described. The technique utilises the vascular anatomy of the spinal cord and brain to provide fixation that is comparable to transcardiac perfusion of the small animal. It can be applied with relative ease, cost effectiveness and without risking premature death of the animal due to complications of a major procedure such as thoracotomy.",

keywords = "Fixatives, Methods, Perfusion fixation, Tissue fixation, Tissue preservation",

author = "Stephen Santoreneos and Stoodley, {Marcus A.} and Jones, {Nigel R.} and Brown, {Chris J.}",

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AU - Santoreneos, Stephen

AU - Stoodley, Marcus A.

AU - Jones, Nigel R.

AU - Brown, Chris J.

PY - 1998/2/20

Y1 - 1998/2/20

N2 - A method for perfusion fixation of the sheep central nervous system is described. The technique utilises the vascular anatomy of the spinal cord and brain to provide fixation that is comparable to transcardiac perfusion of the small animal. It can be applied with relative ease, cost effectiveness and without risking premature death of the animal due to complications of a major procedure such as thoracotomy.

AB - A method for perfusion fixation of the sheep central nervous system is described. The technique utilises the vascular anatomy of the spinal cord and brain to provide fixation that is comparable to transcardiac perfusion of the small animal. It can be applied with relative ease, cost effectiveness and without risking premature death of the animal due to complications of a major procedure such as thoracotomy.

KW - Fixatives

KW - Methods

KW - Perfusion fixation

KW - Tissue fixation

KW - Tissue preservation

UR - http://www.scopus.com/inward/record.url?scp=0032548981&partnerID=8YFLogxK

U2 - 10.1016/S0165-0270(97)00180-5

DO - 10.1016/S0165-0270(97)00180-5

M3 - Article

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JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

IS - 2

ER -

A technique for in vivo vascular perfusion fixation of the sheep central nervous system

Abstract

Keywords

Access to Document

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