TY - JOUR
T1 - Accelerated long-term forgetting of verbal information in unilateral temporal lobe epilepsy
T2 - is it related to structural hippocampal abnormalities and/or incomplete learning?
AU - Lah, Suncica
AU - Mohamed, Armin
AU - Thayer, Zoe
AU - Miller, Laurie
AU - Diamond, Keri
PY - 2014/2/7
Y1 - 2014/2/7
N2 - The factors contributing to accelerated long-term forgetting (ALF) are not yet clear. In this study, a 12-item word list was presented repeatedly to 23 patients with temporal lobe epilepsy (TLE) and 27 control participants (NC) until it was recalled completely on two consecutive trials or until 12 trials were undertaken. Compared to NCs, patients with hippocampal lesions and those who failed to learn the list showed ALF by one day post learning, but the alternative patient groups also showed ALF when tested after seven days. Overall, our findings suggest that in patients with TLE neither a preserved hippocampus nor intact learning protects against ALF.
AB - The factors contributing to accelerated long-term forgetting (ALF) are not yet clear. In this study, a 12-item word list was presented repeatedly to 23 patients with temporal lobe epilepsy (TLE) and 27 control participants (NC) until it was recalled completely on two consecutive trials or until 12 trials were undertaken. Compared to NCs, patients with hippocampal lesions and those who failed to learn the list showed ALF by one day post learning, but the alternative patient groups also showed ALF when tested after seven days. Overall, our findings suggest that in patients with TLE neither a preserved hippocampus nor intact learning protects against ALF.
KW - Memory
UR - http://www.scopus.com/inward/record.url?scp=84894680793&partnerID=8YFLogxK
U2 - 10.1080/13803395.2013.874405
DO - 10.1080/13803395.2013.874405
M3 - Article
C2 - 24479674
AN - SCOPUS:84894680793
SN - 1380-3395
VL - 36
SP - 158
EP - 169
JO - Journal of Clinical and Experimental Neuropsychology
JF - Journal of Clinical and Experimental Neuropsychology
IS - 2
ER -