Accuracy in gamma camera measurements of point source velocities

L. C. Morgan*, M. A. Pearson, D. W. Mackey, J. Rutland, R. U. De Iongh, M. J. Peters, H. Van Der Wall

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Mucociliary clearance is impaired in many diseases of the respiratory system. We have developed a method for measuring tracheal mucus velocity by the dynamic study of a single point source of radioactivity deposited in the trachea by cricothyroid injection. Preliminary results suggest that patients with airways disease have very low tracheal mucus velocities (<2 mm·min-1). The aim of this experiment was to explore the ability of current scintillation detection systems to track a single point as it moves in a dynamic study in small increments and at low velocity (movements of the order of 1 mm). Background noise was estimated to contribute an error in positioning of 0.16 mm (1 standard deviation). Overall errors in velocity were estimated at 0.2 mm·min-1. This suggests that standard instrumentation in use in most nuclear medicine departments has the capacity to measure accurately velocities as low as 1 mm·min-1. (

Original languageEnglish
Pages (from-to)553-556
Number of pages4
JournalNuclear Medicine Communications
Volume21
Issue number6
Publication statusPublished - 2000
Externally publishedYes

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