Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride

Theodorus Van Es, Benjamin Staskun*

*Corresponding author for this work

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Treatment of the title acid successively with SOCl2 and an aqueous amine mixture or with SOCl2 and dry amine yielded, in lieu of the expected 4-oxo amide, the hitherto unreported 4-imino acid and 4-imino amide via a suspected acid chloride-hydrogen chloride complex intermediary.

Original languageEnglish
Pages (from-to)3137-3138
Number of pages2
JournalJournal of the Chemical Society - Perkin Transactions 1
Issue number19
Publication statusPublished - 7 Oct 1998

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