Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride

Theodorus Van Es; Benjamin Staskun

Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride

Theodorus Van Es, Benjamin Staskun^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Treatment of the title acid successively with SOCl₂ and an aqueous amine mixture or with SOCl₂ and dry amine yielded, in lieu of the expected 4-oxo amide, the hitherto unreported 4-imino acid and 4-imino amide via a suspected acid chloride-hydrogen chloride complex intermediary.

Original language	English
Pages (from-to)	3137-3138
Number of pages	2
Journal	Journal of the Chemical Society - Perkin Transactions 1
Issue number	19
Publication status	Published - 7 Oct 1998

Cite this

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title = "Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride",

abstract = "Treatment of the title acid successively with SOCl2 and an aqueous amine mixture or with SOCl2 and dry amine yielded, in lieu of the expected 4-oxo amide, the hitherto unreported 4-imino acid and 4-imino amide via a suspected acid chloride-hydrogen chloride complex intermediary.",

author = "\{Van Es\}, Theodorus and Benjamin Staskun",

year = "1998",

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language = "English",

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journal = "Journal of the Chemical Society - Perkin Transactions 1",

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T1 - Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride

AU - Van Es, Theodorus

AU - Staskun, Benjamin

PY - 1998/10/7

Y1 - 1998/10/7

N2 - Treatment of the title acid successively with SOCl2 and an aqueous amine mixture or with SOCl2 and dry amine yielded, in lieu of the expected 4-oxo amide, the hitherto unreported 4-imino acid and 4-imino amide via a suspected acid chloride-hydrogen chloride complex intermediary.

AB - Treatment of the title acid successively with SOCl2 and an aqueous amine mixture or with SOCl2 and dry amine yielded, in lieu of the expected 4-oxo amide, the hitherto unreported 4-imino acid and 4-imino amide via a suspected acid chloride-hydrogen chloride complex intermediary.

UR - https://www.scopus.com/pages/publications/33749090816

M3 - Article

AN - SCOPUS:33749090816

SN - 0300-922X

SP - 3137

EP - 3138

JO - Journal of the Chemical Society - Perkin Transactions 1

JF - Journal of the Chemical Society - Perkin Transactions 1

IS - 19

ER -

Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride

Abstract

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