Active implant for optoacoustic natural sound enhancement

S. Mohrdiek*, M. Fretz, R. Jose James, G. Spinola Durante, T. Burch, A. Kral, A. Rettenmaier, R. Milani, M. Putkonen, W. Noell, M. Ortsiefer, A. Daly, V. Vinciguerra, C. Garnham, D. Shah

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

Abstract

This paper summarizes the results of an EU project called ACTION: ACTive Implant for Optoacoustic Natural sound enhancement. The project is based on a recent discovery that relatively low levels of pulsed infrared laser light are capable of triggering activity in hair cells of the partially hearing (hearing impaired) cochlea and vestibule. The aim here is the development of a self-contained, smart, highly miniaturized system to provide optoacoustic stimuli directly from an array of miniature light sources in the cochlea. Optoacoustic compound action potentials (oaCAP) are generated by the light source fully inserted into the unmodified cochlea. Previously, the same could only be achieved with external light sources connected to a fiber optic light guide. This feat is achieved by integrating custom made VCSEL arrays at a wavelength of about 1550 nm onto small flexible substrates. The laser light is collimated by a specially designed silicon-based ultra-thin lens (165 um thick) to get the energy density required for the generation of oaCAP signals. A dramatic miniaturization of the packaging technology is also required. A long term biocompatible and hermetic sapphire housing with a size of less than a 1 cubic millimeter and miniature Pt/PtIr feedthroughs is developed, using a low temperature laser assisted process for sealing. A biofouling thin film protection layer is developed to avoid fibrinogen and cell growth on the system.

Original languageEnglish
Title of host publicationOptogenetics and Optical Manipulation
EditorsSamarendra K. Mohanty, Nitish V. Thakor, E. Duco Jansen
PublisherSPIE
Pages1-8
Number of pages8
Volume10052
ISBN (Electronic)9781510605466
ISBN (Print)9781510605459
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes
EventOptogenetics and Optical Manipulation - San Francisco, United States
Duration: 28 Jan 201729 Jan 2017

Publication series

NameProgress in Biomedical Optics and Imaging
PublisherSPIE
Number16
Volume18
ISSN (Print)1605-7422
ISSN (Electronic)2410-9045

Conference

ConferenceOptogenetics and Optical Manipulation
CountryUnited States
CitySan Francisco
Period28/01/1729/01/17

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Keywords

  • Biocompatible
  • Cochlea
  • Hearing loss
  • Hermeticity
  • Laser
  • Miniature package
  • Optical stimulation
  • Optoacoustic effect

Cite this

Mohrdiek, S., Fretz, M., Jose James, R., Spinola Durante, G., Burch, T., Kral, A., ... Shah, D. (2017). Active implant for optoacoustic natural sound enhancement. In S. K. Mohanty, N. V. Thakor, & E. D. Jansen (Eds.), Optogenetics and Optical Manipulation (Vol. 10052, pp. 1-8). [100520K] (Progress in Biomedical Optics and Imaging; Vol. 18, No. 16). SPIE. https://doi.org/10.1117/12.2251912