Acute-phase inflammatory response to single-bout HIIT and endurance training

a comparative study

Felix Kaspar, Harbert F. Jelinek, Steven Perkins, Hayder A. Al-Aubaidy, Bev Dejong, Eugene Butkowski

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13 Citations (Scopus)
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Abstract

Objective. This study compared acute and late effect of single-bout endurance training (ET) and high-intensity interval training (HIIT) on the plasma levels of four inflammatory cytokines and C-reactive protein and insulin-like growth factor 1. Design. Cohort study with repeated-measures design. Methods. Seven healthy untrained volunteers completed a single bout of ET and HIIT on a cycle ergometer. ET and HIIT sessions were held in random order and at least 7 days apart. Blood was drawn before the interventions and 30 min and 2 days after the training sessions. Plasma samples were analyzed with ELISA for the interleukins (IL), IL-1β, IL-6, and IL-10, monocyte chemoattractant protein-1 (MCP-1), insulin growth factor 1 (IGF-1), and C-reactive protein (CRP). Statistical analysis was with Wilcoxon signed-rank tests. Results. ET led to both a significant acute and long-term inflammatory response with a significant decrease at 30 minutes after exercise in the IL-6/IL-10 ratio (-20%; p = 0.047) and a decrease of MCP-1 (-17.9%; p = 0.03). Conclusion. This study demonstrates that ET affects the inflammatory response more adversely at 30 minutes after exercise compared to HIIT. However, this is compensated by a significant decrease in MCP-1 at two days associated with a reduced risk of atherosclerosis.
Original languageEnglish
Article number5474837
Pages (from-to)5474837-1-5474837-6
Number of pages6
JournalMediators of Inflammation
Volume2016
DOIs
Publication statusPublished - 2016

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Copyright the Author(s) 2016. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Cite this

Kaspar, F., Jelinek, H. F., Perkins, S., Al-Aubaidy, H. A., Dejong, B., & Butkowski, E. (2016). Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study. Mediators of Inflammation, 2016, 5474837-1-5474837-6. [5474837]. https://doi.org/10.1155/2016/5474837