Adaptive coding for auditory spatial cues

P. Hehrmann, J. K. Maier, N. S. Harper, D. McAlpine, Maneesh Sahani

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

Abstract

Adaptation of sensory neurons to the prevailing environment is thought to underlie improved coding of relevant stimulus features. Here, we report that neurons in the inferior colliculus (IC) of anesthetized guinea pigs adapt to statistical distributions of interaural time differences (ITDs - one of the binaural cues for sound-source localization). Each distribution contained all of the ITDs in the range of ±330 µs, but with a different high probability range (HPR) of ITDs in each from which ITDs were chosen 80% of the time. The center (mean) or the width (variance) of the HPR was altered systematically to assess the sensitivity of each neuron to the underlying distribution of ITDs. Neural rate-vs.-ITD functions shifted to accommodate the change in the underlying distribution when the mean of the HPR, but not the variance, was altered. Assuming a population of similarly tuned binaural neurons with Poisson spike statistics inputting to an IC neuron, we used an established model of synaptic depression to compute the IC postsynaptic current. By including a stochastic leaky integrate-and-fire mechanism in the IC spike generator, the model predicts the changes in neural gain and the shapes of rate-ITD functions as well as the shifts in Fisher information, a measure of coding accuracy, observed in the physiological data.
Original languageEnglish
Title of host publicationThe Neurophysiological bases of auditory perception
EditorsEnrique A. Lopez-Poveda, Alan R. Palmer, Ray Meddis
Place of PublicationNew York
PublisherSpringer, Springer Nature
Pages357-366
Number of pages10
ISBN (Print)9781441956859
DOIs
Publication statusPublished - 2010
Externally publishedYes
EventInternational Symposium on Hearing (15th : 2009) - Salamanca, Spain
Duration: 1 Jun 20095 Jun 2009

Conference

ConferenceInternational Symposium on Hearing (15th : 2009)
CitySalamanca, Spain
Period1/06/095/06/09

Keywords

  • binaural hearing
  • interaural time differences
  • Fisher information
  • synaptic depression

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  • Cite this

    Hehrmann, P., Maier, J. K., Harper, N. S., McAlpine, D., & Sahani, M. (2010). Adaptive coding for auditory spatial cues. In E. A. Lopez-Poveda, A. R. Palmer, & R. Meddis (Eds.), The Neurophysiological bases of auditory perception (pp. 357-366). New York: Springer, Springer Nature. https://doi.org/10.1007/978-1-4419-5686-6_34