Adociasulfates 1, 7, and 8

new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

John A. Kalaitzis, Priscila de Almeida Leone, Lisa Harris, Mark S. Butler, Anna Ngo, John N. A. Hooper, Ronald J. Quinn*

*Corresponding author for this work

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.

Original languageEnglish
Pages (from-to)5571-5574
Number of pages4
JournalJournal of Organic Chemistry
Volume64
Issue number15
DOIs
Publication statusPublished - 1999
Externally publishedYes

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Kalaitzis, J. A., de Almeida Leone, P., Harris, L., Butler, M. S., Ngo, A., Hooper, J. N. A., & Quinn, R. J. (1999). Adociasulfates 1, 7, and 8: new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp. Journal of Organic Chemistry, 64(15), 5571-5574. https://doi.org/10.1021/jo990404d