Adociasulfates 1, 7, and 8: new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

John A. Kalaitzis; Priscila de Almeida Leone; Lisa Harris; Mark S. Butler; Anna Ngo; John N. A. Hooper; Ronald J. Quinn

doi:10.1021/jo990404d

Adociasulfates 1, 7, and 8: new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

John A. Kalaitzis, Priscila de Almeida Leone, Lisa Harris, Mark S. Butler, Anna Ngo, John N. A. Hooper, Ronald J. Quinn^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.

Original language	English
Pages (from-to)	5571-5574
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	64
Issue number	15
DOIs	https://doi.org/10.1021/jo990404d
Publication status	Published - 1999
Externally published	Yes

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title = "Adociasulfates 1, 7, and 8: new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.",

abstract = "Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.",

author = "Kalaitzis, {John A.} and {de Almeida Leone}, Priscila and Lisa Harris and Butler, {Mark S.} and Anna Ngo and Hooper, {John N. A.} and Quinn, {Ronald J.}",

year = "1999",

doi = "10.1021/jo990404d",

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volume = "64",

pages = "5571--5574",

journal = "Journal of Organic Chemistry",

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T1 - Adociasulfates 1, 7, and 8

T2 - new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

AU - Kalaitzis, John A.

AU - de Almeida Leone, Priscila

AU - Harris, Lisa

AU - Butler, Mark S.

AU - Ngo, Anna

AU - Hooper, John N. A.

AU - Quinn, Ronald J.

PY - 1999

Y1 - 1999

N2 - Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.

AB - Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.

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U2 - 10.1021/jo990404d

DO - 10.1021/jo990404d

M3 - Article

C2 - 11674623

AN - SCOPUS:0033597736

SN - 0022-3263

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SP - 5571

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 15

ER -

Adociasulfates 1, 7, and 8: new bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

Abstract

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