Adult-onset Alexander’s disease mimicking degenerative disease

Omar Ahmad*, Dominic Brock Rowe

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Adult-onset Alexander’s disease is a rare leukodystrophy that can present later in life in a variety of ways, often mimicking more common neurodegenerative conditions. We present two cases with novel mutations, diagnosed from their characteristic MR scan findings. Even in much older people, clinicians should have a high clinical suspicion if there are typical imaging findings.

Original languageEnglish
Pages (from-to)393-395
Number of pages3
JournalPractical Neurology
Issue number5
Publication statusPublished - 1 Oct 2015


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