Advances on aryldiazonium salt chemistry based interfacial fabrication for sensing applications

Chaomin Cao, Yin Zhang, Cheng Jiang, Meng Qi, Guozhen Liu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

95 Citations (Scopus)


Aryldiazonium salts as coupling agents for surface chemistry have evidenced their wide applications for the development of sensors. Combined with advances in nanomaterials, current trends in sensor science and a variety of particular advantages of aryldiazonium salt chemistry in sensing have driven the aryldiazonium salt-based sensing strategies to grow at an astonishing pace. This review focuses on the advances in the use of aryldiazonium salts for modifying interfaces in sensors and biosensors during the past decade. It will first summarize the current methods for modification of interfaces with aryldiazonium salts, and then discuss the sensing applications of aryldiazonium salts modified on different transducers (bulky solid electrodes, nanomaterials modified bulky solid electrodes, and nanoparticles). Finally, the challenges and perspectives that aryldiazonium salt chemistry is facing in sensing applications are critically discussed.
Original languageEnglish
Pages (from-to)5031-5049
Number of pages19
JournalACS Applied Materials and Interfaces
Issue number6
Publication statusPublished - 15 Feb 2017


  • aryldiazonium salts
  • sensing applications
  • nanomaterials
  • nanosensors
  • interface fabrication


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