Age-related urologic problems in the complex urologic patient

Nicholas Faure Walker*, Bradley Gill, Jonathan Olsburgh, David Gillatt, Tet Yap, Lina Michala, Claire Taylor, Hadley Wood, Dan Wood

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Purpose: Improved medical care throughout childhood and adolescence has enabled patients with complex urological abnormalities to live longer into adulthood. These patients are now at risk of developing common, age-related, urological conditions. This review aims to review existing data and make recommendations in areas where expert opinion is currently lacking Methods: This review represents the joint SIU-ICUD (Société Internationale d’Urologie-International Consultation on Urological Disease) consultation on congenital lifelong urology. The results of this analysis were first presented at a joint consultation of the ICUD and SIU at the 2018 SIU annual conference in Seoul, South Korea. Results: BPH may present differently in patients with neurogenic bladder. Thorough assessment of neurological status, bladder and sphincter function is required before offering any bladder outlet surgery. Prostate specific antigen screening should be offered to men aged 50–69 with neurogenic bladders if they have good life expectancy. Multi-parametric MRI and transperineal biopsy would be the investigations of choice if feasible. Surgery for localized disease should only be done by surgeons with the relevant expertise. Bladder cancer in this patient group is more likely to present at a later stage and have a worse prognosis. Parenthood is achievable for most, but often requires assistance with conception. Pregnant women who have had previous urogenital reconstructive surgery should be managed in appropriate obstetric units with the involvement of a reconstructive urologist. Conclusions: Most evidence regarding complex urogenital abnormalities comes from the pediatric population. Evidence regarding common, age-related urological issues is generally from the ‘normal’ adult population. As patients with complex congenital urological conditions live longer, more data will become available to assess the long-term benefits of intervention.

Original languageEnglish
Pages (from-to)1037-1044
Number of pages8
JournalWorld Journal of Urology
Issue number4
Early online date15 Feb 2020
Publication statusPublished - Apr 2021


  • Hypogonadism
  • Neurogenic bladder
  • Prostate cancer
  • Urology


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