All-in-one thermometer-heater up-converting platform YF3:Yb3+,Tm3+ operating in the first biological window

Hao Suo, Fangfang Hu, Xiaoqi Zhao, Zhiyu Zhang, Ting Li, Changkui Duan, Min Yin, Chongfeng Guo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

107 Citations (Scopus)


Achieving the combination of real-time diagnosis and therapy in one up-converting platform with sensitive thermometry and efficient heat production is a critical step towards photo-thermal therapy (PTT). Here, the potentiality of truncated octahedral YF3:Tm3+/Yb3+ micro-crystals as thermometers operating in the first biological window (BW-I) was evaluated on the basis of a thermo-responsive fluorescence intensity ratio (FIR) of far-red to NIR emission from completely separated 3F2,3/3H43H6 transitions. The probabilities of cross-relaxation (CR) processes related to 3F2,3/3H4 levels were greatly enhanced by increasing the Yb3+ content, leading to an increase of more than three times in the absolute sensitivity within the physiological temperature range. Photo-thermal effects were also assessed by monitoring the variation of temperature around the samples as functions of the Yb3+ dosage, excitation time and density of 980 nm laser diodes. These results offer a promising strategy to optimize the thermal sensitivity and optical heating ability, which indicates that the present UC platform has great potential applications in PTT as real-time thermometers and photo-thermal agents.

Original languageEnglish
Pages (from-to)1501-1507
Number of pages7
JournalJournal of Materials Chemistry C
Issue number6
Publication statusPublished - 2017
Externally publishedYes


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