Allogeneic bone marrow transplant for refractory mediastinal germ cell tumour

Possible evidence of graft-versus-tumour effect

A. Goodwin*, H. Gurney, D. Gottlieb

*Corresponding author for this work

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Mediastinal germ cell tumours (GCT) carry a poor prognosis, particularly after relapse. We have reviewed the published reports of current treatments and describe a case with a cure after an allogeneic bone marrow transplant, which is not reported in the current published data. We believe that GCT may be susceptible to a graft-versus-tumour effect and suggest that patients with relapsed GCT be considered for allogeneic transplantation.

Original languageEnglish
Pages (from-to)127-129
Number of pages3
JournalInternal Medicine Journal
Volume37
Issue number2
DOIs
Publication statusPublished - Feb 2007
Externally publishedYes

Keywords

  • Allogeneic bone marrow transplant
  • Graft-versus-tumour effect
  • Relapsed extragonadal germ cell tumour

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