TY - JOUR
T1 - Allogeneic bone marrow transplant for refractory mediastinal germ cell tumour
T2 - Possible evidence of graft-versus-tumour effect
AU - Goodwin, A.
AU - Gurney, H.
AU - Gottlieb, D.
PY - 2007/2
Y1 - 2007/2
N2 - Mediastinal germ cell tumours (GCT) carry a poor prognosis, particularly after relapse. We have reviewed the published reports of current treatments and describe a case with a cure after an allogeneic bone marrow transplant, which is not reported in the current published data. We believe that GCT may be susceptible to a graft-versus-tumour effect and suggest that patients with relapsed GCT be considered for allogeneic transplantation.
AB - Mediastinal germ cell tumours (GCT) carry a poor prognosis, particularly after relapse. We have reviewed the published reports of current treatments and describe a case with a cure after an allogeneic bone marrow transplant, which is not reported in the current published data. We believe that GCT may be susceptible to a graft-versus-tumour effect and suggest that patients with relapsed GCT be considered for allogeneic transplantation.
KW - Allogeneic bone marrow transplant
KW - Graft-versus-tumour effect
KW - Relapsed extragonadal germ cell tumour
UR - http://www.scopus.com/inward/record.url?scp=33846092015&partnerID=8YFLogxK
U2 - 10.1111/j.1445-5994.2007.01244.x
DO - 10.1111/j.1445-5994.2007.01244.x
M3 - Review article
C2 - 17229257
AN - SCOPUS:33846092015
SN - 1444-0903
VL - 37
SP - 127
EP - 129
JO - Internal Medicine Journal
JF - Internal Medicine Journal
IS - 2
ER -