Allogeneic bone marrow transplant for refractory mediastinal germ cell tumour: Possible evidence of graft-versus-tumour effect

A. Goodwin, H. Gurney, D. Gottlieb

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

Mediastinal germ cell tumours (GCT) carry a poor prognosis, particularly after relapse. We have reviewed the published reports of current treatments and describe a case with a cure after an allogeneic bone marrow transplant, which is not reported in the current published data. We believe that GCT may be susceptible to a graft-versus-tumour effect and suggest that patients with relapsed GCT be considered for allogeneic transplantation.

LanguageEnglish
Pages127-129
Number of pages3
JournalInternal Medicine Journal
Volume37
Issue number2
DOIs
Publication statusPublished - Feb 2007
Externally publishedYes

Fingerprint

Germ Cell and Embryonal Neoplasms
Bone Marrow
Transplants
Neoplasms
Homologous Transplantation
Recurrence
Therapeutics

Keywords

  • Allogeneic bone marrow transplant
  • Graft-versus-tumour effect
  • Relapsed extragonadal germ cell tumour

Cite this

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Allogeneic bone marrow transplant for refractory mediastinal germ cell tumour : Possible evidence of graft-versus-tumour effect. / Goodwin, A.; Gurney, H.; Gottlieb, D.

In: Internal Medicine Journal, Vol. 37, No. 2, 02.2007, p. 127-129.

Research output: Contribution to journalReview articleResearchpeer-review

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