Alzheimer’s disease and other neurodegenerative diseases

Stephanie J. Fuller, Hamid R. Sohrabi, Kathryn G. Goozee, Anoop Sankaranarayanan, Ralph N. Martins

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)

Abstract

Neurodegenerative diseases are a heterogeneous group of disorders or conditions characterised by the progressive degeneration of the structure and function of the central nervous system or the peripheral nervous system. Some are considered to be caused by protein misfolding, some involve disruptions to intracellular processes such as mitochondrial function or protein degradation pathways, and some are genetic in origin. Whatever the original cause of the disease, the greatest risk factor for most of these diseases is increasing age. This book is mostly focused on Alzheimer’s disease (AD), yet in this chapter we describe Alzheimer’s as well as other major neurodegenerative conditions to demonstrate both similarities and differences.

Original languageEnglish
Title of host publicationNeurodegeneration and Alzheimer’s disease
Subtitle of host publicationthe role of diabetes, genetics, hormones, and lifestyle
EditorsRalph N. Martins, Charles S. Brennan
Place of PublicationHoboken, NJ
PublisherWiley
Chapter2
Pages11-42
Number of pages32
ISBN (Electronic)9781119356752
ISBN (Print)9781119356783
DOIs
Publication statusPublished - 11 May 2019

Keywords

  • Alzheimer’s disease
  • Cardiovascular disease
  • Disease pathology
  • Lifestyle changes
  • Neurodegenerative conditions
  • Parkinson’s disease
  • Type 2 diabetes
  • Vascular dementia

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