Amplified detection signal at a photoelectrochemical aptasensor with a poly(diphenylbutadiene)-BiOBr heterojunction and Au-modified CeO2 octahedrons

Hejie Zheng, Si Zhang, Jiangfeng Yuan, Tengteng Qin, Tongtong Li, Yuping Sun, Xiaoqiang Liu*, Danny K. Y. Wong*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A major aspect of this work is the synergistic application of a poly(diphenylbutadiene)-BiOBr composite and a gold nanoparticle-linked CeO2 octahedron to develop a photoelectrochemical aptasensor with an easily measurable detection signal change. Specifically, poly(diphenylbutadiene) nanofiber-immobilised BiOBr flower-like microspheres were developed as a hybrid material with a heterojunction that facilitates high visible light absorption and efficient photo-generated charge separation, which are essential features for sensitive photoelectrochemical sensors. The model analyte acetamiprid was attached via its specific aptamer on the aptasensor. Separately, a gold nanoparticle-linked CeO2 octahedron was strategically used to significantly diminish the photocurrent by impeding electron transfer at the aptasensor surface. After acetamiprid binding, the CeO2 octahedrons were displaced from the aptasensor. This caused a weakened quenching effect and restored the photocurrent to accomplish an “on-off-on” detection mechanism. This photoelectrochemical aptasensor exhibited a detection limit of 0.05 pM over a linear range of 0.1 pM–10 μM acetamiprid. The use of an aptamer has provided good specificity to acetamiprid and anti-interference. In addition, an ∼5.8% relative standard deviation was estimated as the reproducibility of the photoelectrochemical aptasensor. Furthermore, nearly 90% of the initial photocurrent was still measurable after storing these aptasensors at room temperature for 4 weeks, demonstrating their stability.

    Original languageEnglish
    Article number113742
    Pages (from-to)1-8
    Number of pages8
    JournalBiosensors and Bioelectronics
    Volume197
    DOIs
    Publication statusPublished - 1 Feb 2022

    Keywords

    • Photoelectrochemical aptasensor
    • Poly(diphenylbutadiene)
    • Bismuth bromoxide
    • Au-modified CeO octahedrons
    • Acetamiprid

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