Amplified single molecule detection in a thermoplastic microfluidic system

Jonas Jarvius, Jonas Melin*, Jenny Göransson, Henrik Johansson, Fredrik Nikolajeff, Ulf Landegren, Mats Nilsson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

Abstract

In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.

Original languageEnglish
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages712-714
Number of pages3
Volume1
ISBN (Print)0974361119, 9780974361116
Publication statusPublished - 2005
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: 9 Oct 200513 Oct 2005

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period9/10/0513/10/05

Keywords

  • Bacteria
  • Digital detection
  • Injection molding
  • Single molecule detection

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