Amplified single molecule detection in a thermoplastic microfluidic system

Jonas Jarvius, Jonas Melin*, Jenny Göransson, Henrik Johansson, Fredrik Nikolajeff, Ulf Landegren, Mats Nilsson

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

    Abstract

    In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.

    Original languageEnglish
    Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
    PublisherTransducer Research Foundation
    Pages712-714
    Number of pages3
    Volume1
    ISBN (Print)0974361119, 9780974361116
    Publication statusPublished - 2005
    Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
    Duration: 9 Oct 200513 Oct 2005

    Other

    Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
    CountryUnited States
    CityBoston, MA
    Period9/10/0513/10/05

    Keywords

    • Bacteria
    • Digital detection
    • Injection molding
    • Single molecule detection

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