Amplified single molecule detection in a thermoplastic microfluidic system

Jonas Jarvius; Jonas Melin; Jenny Göransson; Henrik Johansson; Fredrik Nikolajeff; Ulf Landegren; Mats Nilsson

Amplified single molecule detection in a thermoplastic microfluidic system

Jonas Jarvius, Jonas Melin^*, Jenny Göransson, Henrik Johansson, Fredrik Nikolajeff, Ulf Landegren, Mats Nilsson

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

Abstract

In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.

Original language	English
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Transducer Research Foundation
Pages	712-714
Number of pages	3
Volume	1
ISBN (Print)	0974361119, 9780974361116
Publication status	Published - 2005
Event	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States Duration: 9 Oct 2005 → 13 Oct 2005

Other

Other	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Country/Territory	United States
City	Boston, MA
Period	9/10/05 → 13/10/05

Keywords

Bacteria
Digital detection
Injection molding
Single molecule detection

Cite this

Jarvius, J., Melin, J., Göransson, J., Johansson, H., Nikolajeff, F., Landegren, U., & Nilsson, M. (2005). Amplified single molecule detection in a thermoplastic microfluidic system. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Vol. 1, pp. 712-714). Transducer Research Foundation.

@inproceedings{84a83991a6e848a8b9078715aeef9912,

title = "Amplified single molecule detection in a thermoplastic microfluidic system",

abstract = "In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.",

keywords = "Bacteria, Digital detection, Injection molding, Single molecule detection",

author = "Jonas Jarvius and Jonas Melin and Jenny G{\"o}ransson and Henrik Johansson and Fredrik Nikolajeff and Ulf Landegren and Mats Nilsson",

year = "2005",

language = "English",

isbn = "0974361119",

volume = "1",

pages = "712--714",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Transducer Research Foundation",

note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",

}

Jarvius, J, Melin, J, Göransson, J, Johansson, H, Nikolajeff, F, Landegren, U & Nilsson, M 2005, Amplified single molecule detection in a thermoplastic microfluidic system. in Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. vol. 1, Transducer Research Foundation, pp. 712-714, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005, Boston, MA, United States, 9/10/05.

Amplified single molecule detection in a thermoplastic microfluidic system. / Jarvius, Jonas; Melin, Jonas; Göransson, Jenny et al.
Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1 Transducer Research Foundation, 2005. p. 712-714.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - Amplified single molecule detection in a thermoplastic microfluidic system

AU - Jarvius, Jonas

AU - Melin, Jonas

AU - Göransson, Jenny

AU - Johansson, Henrik

AU - Nikolajeff, Fredrik

AU - Landegren, Ulf

AU - Nilsson, Mats

PY - 2005

Y1 - 2005

N2 - In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.

AB - In this abstract we present detection of single DNA molecules in a thermoplastic microfluidic system. This is possible due to a localized enzymatic amplification mechanism termed rolling circle amplification (RCA) and a microchannel made of the optical polymer Zeonor.

KW - Bacteria

KW - Digital detection

KW - Injection molding

KW - Single molecule detection

UR - http://www.scopus.com/inward/record.url?scp=84902477398&partnerID=8YFLogxK

M3 - Conference proceeding contribution

AN - SCOPUS:84902477398

SN - 0974361119

SN - 9780974361116

VL - 1

SP - 712

EP - 714

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Transducer Research Foundation

T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005

Y2 - 9 October 2005 through 13 October 2005

ER -

Jarvius J, Melin J, Göransson J, Johansson H, Nikolajeff F, Landegren U et al. Amplified single molecule detection in a thermoplastic microfluidic system. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1. Transducer Research Foundation. 2005. p. 712-714

Amplified single molecule detection in a thermoplastic microfluidic system

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