An approach of computational hemodynamics for cardiovascular flow simulation

J. L. Liu, Y. Qian, K. Itatani, T. Miyakoshi, A. Murakami, M. Ono, R. Shiurba, K. Miyaji, M. Umezu

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

    10 Citations (Scopus)


    Computational fluid dynamics (CFD) is one of available methods to quantitatively evaluate the treatments of cardiovascular disease. However, currently, applications of this technology to cardiac surgery are few due to the complexity of performing physiological simulation. Here, we used CFD to study the outcome of the Norwood surgical procedure for palliating hypoplastic left heart syndrome in a 33-month-old child. The Reynolds number for post-surgical flow calculated at the peak of systole was about 4000, consistent with turbulent flow. During diastole, by contrast, the flow reduced to low speed, suggesting the strong transition flow from systole to diastole. Therefore, to improve the simulation of transitional flow, we determined that time step intervals of 10-5 second were best in using the k-ε turbulence model. We also develop a new boundary condition to simulate blood pressure wave reflection from peripheral vessels in order to physiologically capture pressure recovery and correctly obtained flow through each arch-branch and flow pattern in the coronary. Then we computed time-varying energy losses, local pressure, and wall shear stress at the anastomosis to evaluate the surgical outcome. The results suggest the time step and boundary conditions that take account of pressure wave reflection improve simulation of cardiovascular flow.

    Original languageEnglish
    Title of host publicationProceedings of ASME-JSME-KSME Joint Fluids Engineering Conference 2011 (AJK2011-FED)
    Place of PublicationJapan
    PublisherAmerican Society of Mechanical Engineers (ASME)
    Number of pages8
    EditionPARTS A, B, C, D
    ISBN (Print)9780791844403
    Publication statusPublished - 2011
    EventASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011 - Hamamatsu, Japan
    Duration: 24 Jul 201129 Jul 2011


    OtherASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011

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