An Australian trial of ThinPrep: a new cytopreparatory technique

C. R A LAVERTY*, J. K. THURLOE, N. L. REDMAN, A. FARNSWORTH

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

To evaluate the sensitivity and suitability of ThinPrep, a new slide preparation technique, 2026 paired cervical cytology slides were examined. After conventional Papanicolaou smears were prepared, the sampling instruments were rinsed in a fluid fixative. ThinPrep slides were then prepared in the laboratory from the surplus cells in the fixative. Compared with the Pap smears, ThinPrep slides were easier and quicker to screen, were inconclusive less often, and had similar rates for detecting abnormalities and infection. There were more unsatisfactory ThinPrep slides and more ThinPrep slides lacked endocervical cells. Both of these shortcomings were found to be linked to the choice of sampling implements. This study, in which a variety of sampling instruments was used, fails to confirm some of the previous claims made for the new technique.

Original languageEnglish
Pages (from-to)140-148
Number of pages9
JournalCytopathology
Volume6
Issue number3
DOIs
Publication statusPublished - 1995
Externally publishedYes

Keywords

  • Papanicolaou smear
  • sampling instruments
  • thinPrep

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