An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo, Macropus rufus

Jennifer A. Donald*, M. A. Adams

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials.

Original languageEnglish
Pages (from-to)901-908
Number of pages8
JournalBiochemical Genetics
Volume19
Issue number9-10
DOIs
Publication statusPublished - Oct 1981
Externally publishedYes

Keywords

  • autosomal gene assignment
  • LDH-A
  • marsupial
  • somatic cell hybrids

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