An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo, Macropus rufus

Jennifer A. Donald; M. A. Adams

doi:10.1007/BF00504255

An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo, Macropus rufus

Jennifer A. Donald^*, M. A. Adams

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials.

Original language	English
Pages (from-to)	901-908
Number of pages	8
Journal	Biochemical Genetics
Volume	19
Issue number	9-10
DOIs	https://doi.org/10.1007/BF00504255
Publication status	Published - Oct 1981
Externally published	Yes

Keywords

autosomal gene assignment
LDH-A
marsupial
somatic cell hybrids

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10.1007/BF00504255

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title = "An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo, Macropus rufus",

abstract = "A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials.",

keywords = "autosomal gene assignment, LDH-A, marsupial, somatic cell hybrids",

author = "Donald, {Jennifer A.} and Adams, {M. A.}",

year = "1981",

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doi = "10.1007/BF00504255",

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AU - Adams, M. A.

PY - 1981/10

Y1 - 1981/10

N2 - A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials.

AB - A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials.

KW - autosomal gene assignment

KW - LDH-A

KW - marsupial

KW - somatic cell hybrids

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JO - Biochemical Genetics

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IS - 9-10

ER -

An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo, Macropus rufus

Abstract

Keywords

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