An causal XAI diagnostic model for breast cancer based on mammography reports

Dehua Chen, Hongjin Zhao, Jianrong He, Qiao Pan, Weiliang Zhao

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

19 Citations (Scopus)

Abstract

Breast cancer has become one of the most common malignant tumors in women worldwide, and it seriously threatens women's physical and mental health. In recent years, with the development of Artificial Intelligence(AI) and the accumulation of medical data, AI has begun to be deeply integrated with mammography, MRI, ultrasound, etc. to assist physicians in disease diagnosis. However, the existing breast cancer diagnosis model based on Computer Vision(CV) is greatly affected by the image quality; on the other hand, the breast cancer diagnosis model based on Natural Language Processing(NLP) cannot effectively extract the semantic information of the mammography report. The lack of model interpretability also makes the existing diagnostic models have low confidence. In this paper, we proposed Breast Cancer Causal XAI Diagnostic Model(BCCXDM). Specifically, we first structured the mammography report. Then find the causal graph based on the structured table. We combine the existing tabular learning method TabNet with causal graphs(Causal-TabNet) to enable reasoning in the graphs to preserve the correlation between features. More importantly, we use GNN and node transition probability to aggregate node information. We evaluate our model on the real-world mammography report, and compare it with other popular interpretable methods. The experimental results show that our interpretable results are closer to the diagnostic criteria of clinicians

Original languageEnglish
Title of host publicationProceedings - 2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021
EditorsYufei Huang, Lukasz Kurgan, Feng Luo, Xiaohua Tony Hu, Yidong Chen, Edward Dougherty, Andrzej Kloczkowski, Yaohang Li
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages3341-3349
Number of pages9
ISBN (Electronic)9781665401265
DOIs
Publication statusPublished - 2021
Event2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021 - Virtual, Online, United States
Duration: 9 Dec 202112 Dec 2021

Conference

Conference2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021
Country/TerritoryUnited States
CityVirtual, Online
Period9/12/2112/12/21

Keywords

  • breast cancer
  • interpretability
  • mammography report
  • causal graph

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