An enhanced miniaturized assay for antimicrobial prospecting

Shannon M. Smith*, Andrew J. Beattie, Michael R. Gillings, Marita P. Holley, Adam J. Stow, Christine L. Turnbull, Peter D. Wilson, David A. Briscoe

*Corresponding author for this work

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalJournal of Microbiological Methods
Volume72
Issue number1
DOIs
Publication statusPublished - Jan 2008

Keywords

  • antimicrobials
  • assay
  • bioprospecting
  • microtitre

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