Purpose: This study attempted to define an optimum animal model for neonatal thoracoscopy. Materials and Methods: Seven rabbits and three 5-7-kg piglets were subjected to thoracoscopy by three pediatric surgeons. The outcome for the successful completion of esophageal anastomosis and additional procedures, including diaphragmatic plication and lung biopsy, were noted. Results: Whereas esophageal anastomosis could be accomplished in all piglets, it could be achieved in only 1 rabbit. Additional procedures were possible in 2 piglets and no rabbits. Anesthetic complications were seen in 4 rabbits and 1 piglet. Conclusion: Our findings suggest that the piglet may be the optimum animal model for replicating neonatal thoracoscopy. The fragility of the rabbit, coupled with a limited intrathoracic working space, limits its use for thoracoscopy.
|Number of pages||4|
|Journal||Journal of laparoendoscopic and advanced surgical techniques|
|Publication status||Published - 2008|
Jones, V. S., Wood, J. G., Godfrey, C., & Cohen, R. C. (2008). An optimum animal model for neonatal thoracoscopy. Journal of laparoendoscopic and advanced surgical techniques, 18(5), 759-762. https://doi.org/10.1089/lap.2007.0224