An optimum animal model for neonatal thoracoscopy

Vinci S. Jones, James G. Wood, Craig Godfrey, Ralph C. Cohen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: This study attempted to define an optimum animal model for neonatal thoracoscopy. Materials and Methods: Seven rabbits and three 5-7-kg piglets were subjected to thoracoscopy by three pediatric surgeons. The outcome for the successful completion of esophageal anastomosis and additional procedures, including diaphragmatic plication and lung biopsy, were noted. Results: Whereas esophageal anastomosis could be accomplished in all piglets, it could be achieved in only 1 rabbit. Additional procedures were possible in 2 piglets and no rabbits. Anesthetic complications were seen in 4 rabbits and 1 piglet. Conclusion: Our findings suggest that the piglet may be the optimum animal model for replicating neonatal thoracoscopy. The fragility of the rabbit, coupled with a limited intrathoracic working space, limits its use for thoracoscopy.
Original languageEnglish
Pages (from-to)759-762
Number of pages4
JournalJournal of laparoendoscopic and advanced surgical techniques
Volume18
Issue number5
DOIs
Publication statusPublished - 2008
Externally publishedYes

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