Analysis of datasets showing which compounds kill which organisms

inferring two systems

T. Paul Hutchinson

Research output: Contribution to journalArticle

Abstract

Experiments are sometimes conducted to show which of several compounds is successful at inactivating which of several microorganisms. This paper proposes a method of analysing the datasets obtained. The example refers to 33 compounds (2,4-dihydroxythiobenzanilides) and seven microorganisms (dermatophytes) [data from Eur. J. Med. Chem. 35 (2000) 393]. The conclusion is that two systems or modes of action are needed to explain the data.
Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalEuropean Journal of Medicinal Chemistry
Volume39
Issue number1
DOIs
Publication statusPublished - 2004

Keywords

  • 2,4-Dihydroxythiobenzanilides
  • Antifungal activity
  • Data condensation
  • Dermatophytes

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