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Anatomy, pathophysiology and assessment of upper‑body lymphoedema

Sandi Davis, Suzie Ehmann, Brandy McKeown, Neil Piller, Joseph Dayan, Hiroo Suami, Justine C. Whitaker, Karen J. Bock

Research output: Contribution to journalReview articlepeer-review

Abstract

This article reviews the lymphatic system’s anatomy and physiology, as well as the etiology of lymphoedema affecting the upper limbs, breast and trunk. It presents evidence-based strategies for assessment, including history-taking, physical exams and clinical tests to guide treatment planning. The importance of selecting personalised compression garments is emphasised. Legislative impacts—such as the US 2024 Lymphedema Treatment Act—and global variability in compression therapy funding are explored, along with nuanced approaches to assessment, staging and diagnostic criteria.
Original languageEnglish
Pages (from-to)S5-S18
Number of pages14
JournalJournal of Wound Care
Volume34
Issue number11 Sup C
DOIs
Publication statusPublished - 1 Nov 2025

Keywords

  • Lymphoedema
  • Lymphatic anatomy
  • Compression therapy
  • STRIDE framework
  • ICG lymphography
  • Lymphatic drainage
  • Pathophysiology
  • Breast and trunk lymphoedema
  • Comorbidities
  • Assessment and diagnosis

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