Angiotensin II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla

Yu Wen Li*, J. W. Polson, R. A L Dampney

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, l-glutamate injections into the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.

Original languageEnglish
Pages (from-to)161-164
Number of pages4
JournalBrain Research
Volume577
Issue number1
DOIs
Publication statusPublished - 10 Apr 1992
Externally publishedYes

Keywords

  • Angiotensin
  • l-Glutamate
  • Respiratory activity
  • Vasomotor activity
  • Ventrolateral medulla

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