Angiotensin II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla

Yu Wen Li; J. W. Polson; R. A L Dampney

doi:10.1016/0006-8993(92)90551-J

Angiotensin II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla

Yu Wen Li^*, J. W. Polson, R. A L Dampney

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, l-glutamate injections into the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.

Original language	English
Pages (from-to)	161-164
Number of pages	4
Journal	Brain Research
Volume	577
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(92)90551-J
Publication status	Published - 10 Apr 1992
Externally published	Yes

Keywords

Angiotensin
l-Glutamate
Respiratory activity
Vasomotor activity
Ventrolateral medulla

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10.1016/0006-8993(92)90551-J

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title = "Angiotensin II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla",

abstract = "We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, l-glutamate injections into the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.",

keywords = "Angiotensin, l-Glutamate, Respiratory activity, Vasomotor activity, Ventrolateral medulla",

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AU - Li, Yu Wen

AU - Polson, J. W.

AU - Dampney, R. A L

PY - 1992/4/10

Y1 - 1992/4/10

N2 - We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, l-glutamate injections into the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.

AB - We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, l-glutamate injections into the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.

KW - Angiotensin

KW - l-Glutamate

KW - Respiratory activity

KW - Vasomotor activity

KW - Ventrolateral medulla

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JO - Brain Research

JF - Brain Research

SN - 0006-8993

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ER -

Angiotensin II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla

Abstract

Keywords

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