TY - JOUR
T1 - Anterior lumbar interbody fusion versus transforaminal lumbar interbody fusion
T2 - systematic review and meta-analysis
AU - Phan, Kevin
AU - Thayaparan, Ganesha K.
AU - Mobbs, Ralph J.
PY - 2015/9/3
Y1 - 2015/9/3
N2 - Purpose. To assess the clinical and radiographic outcomes and complications of anterior lumbar interbody fusion (ALIF) versus transforaminal lumbar interbody fusion (TLIF). Methods. A systematic literature search was conducted from six electronic databases. The relative risk and weighted mean difference (WMD) were used as statistical summary effect sizes. Results. Fusion rates (88.6% vs. 91.9%, P = 0.23) and clinical outcomes were comparable between ALIF and TLIF. ALIF was associated with restoration of disk height (WMD, 2.71 mm, P = 0.01), segmental lordosis (WMD, 2.35, P = 0.03), and whole lumbar lordosis (WMD, 6.33, P = 0.03). ALIF was also associated with longer hospitalization (WMD, 1.8 days, P = 0.01), lower dural injury (0.4% vs. 3.8%, P = 0.05) but higher blood vessel injury (2.6% vs. 0%, P = 0.04). Conclusions. ALIF and TLIF appear to have similar success and clinical outcomes, with different complication profiles. ALIF may be associated with superior restoration of disk height and lordosis, but requires further validation in future studies.
AB - Purpose. To assess the clinical and radiographic outcomes and complications of anterior lumbar interbody fusion (ALIF) versus transforaminal lumbar interbody fusion (TLIF). Methods. A systematic literature search was conducted from six electronic databases. The relative risk and weighted mean difference (WMD) were used as statistical summary effect sizes. Results. Fusion rates (88.6% vs. 91.9%, P = 0.23) and clinical outcomes were comparable between ALIF and TLIF. ALIF was associated with restoration of disk height (WMD, 2.71 mm, P = 0.01), segmental lordosis (WMD, 2.35, P = 0.03), and whole lumbar lordosis (WMD, 6.33, P = 0.03). ALIF was also associated with longer hospitalization (WMD, 1.8 days, P = 0.01), lower dural injury (0.4% vs. 3.8%, P = 0.05) but higher blood vessel injury (2.6% vs. 0%, P = 0.04). Conclusions. ALIF and TLIF appear to have similar success and clinical outcomes, with different complication profiles. ALIF may be associated with superior restoration of disk height and lordosis, but requires further validation in future studies.
KW - ALIF
KW - anterior lumbar interbody fusion
KW - fusion
KW - lumbar spondylosis
KW - TLIF
KW - transforaminal lumbar interbody fusion
UR - http://www.scopus.com/inward/record.url?scp=84949463013&partnerID=8YFLogxK
U2 - 10.3109/02688697.2015.1036838
DO - 10.3109/02688697.2015.1036838
M3 - Review article
C2 - 25968330
AN - SCOPUS:84949463013
VL - 29
SP - 705
EP - 711
JO - British Journal of Neurosurgery
JF - British Journal of Neurosurgery
SN - 0268-8697
IS - 5
ER -