Antibiotic enhanced dopamine polymerization for engineering antifouling and antimicrobial membranes

Shuaifei Zhao*, Maryam Golestani, Anahit Penesyan, Baolin Deng, Chunmiao Zheng, Vladimir Strezov

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    49 Citations (Scopus)


    In this work, we adopt a new tobramycin (TOB)-dopamine coating system to endow thin film composite membranes with excellent antifouling and antimicrobial properties. Combining the hydrophilic and antibiofouling properties of both TOB and polydopamine, the TOB-dopamine modified membrane exhibits improved antifouling and antimicrobial properties compared with the conventional dopamine modified and unmodified membranes. The TOB-dopamine system has two advantages over the conventional modification with dopamine and tris buffer solution. First, TOB-dopamine modification is more efficient than the conventional dopamine modification due to the accelerating effect of TOB on dopamine polymerization. Second, the TOB-dopamine modified membranes exhibit better hydrophilicity, and enhanced antifouling and antimicrobial properties than the conventional dopamine modified membrane. Beyond engineering membranes, the proposed TOB-dopamine system can also be extended for wider surface hydrophilic and antimicrobial modifications.

    Original languageEnglish
    Pages (from-to)851-854
    Number of pages4
    JournalChinese Chemical Letters
    Issue number3
    Early online date29 May 2019
    Publication statusPublished - Mar 2020


    • Dopamine
    • Membrane fouling
    • Antimicrobial
    • Membranes
    • Surface modification


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