Antidiabetic, antihypertensive and statin medication use in metabolic syndrome

E. Ie Butkowski; L. Brix; H. A. Al-Aubaidy; Hosen Kiat; H. F. Jelinek

doi:10.17352/ijpsdr.000005

Antidiabetic, antihypertensive and statin medication use in metabolic syndrome

E. Ie Butkowski, L. Brix, H. A. Al-Aubaidy, Hosen Kiat, H. F. Jelinek^*

^*Corresponding author for this work

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Abstract

Background: Metabolic syndrome (MetS) is characterised by a cluster of metabolic risk factors, which eventually increases the risk of diabetes and cardiovascular disease (CVD). The aim of the current study was to investigate medication use in outpatient communities with respect to the occurrence of these metabolic risk factors as defined by ATPIII. Methods: Data for this study was obtained from patients attending a diabetes health screening clinic (DiabHealth) in south-eastern Australia between 2005 and 2011. Participants had a medical history taken and anthropomorphic data collected. Participants with three or more MetS factors were classified as MetS positive as outlined by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Results: Antidiabetic, antihypertensive and antihyperlipidaemic use varies significantly in uptake by participants and with respect to the number of ATPIII factors present. Blood glucose levels (BGL) and the female waist circumference were significantly better in the MetS compared to the non-MetS group. The most increase in medication use in the MetS group was seen for antidiabetic medication (21.3% versus 2.4%, p < 0.01) compared to the non-MetS group. Antihypertensive use tripled (67.8% vs. 26.03%) and Statin use doubled significantly (p<0.01) in the MetS group (21.8% vs. 8.9%). Conclusion: Medication use increases with an increase in ATPIII factors present in the study. Participants with increased BGL (>6.1mmol/L) were not found to have antihyperglycemic medication prescribed. However both antihypertensive medication and Statins were extensively prescribed in cases where only 1 and 2 ATP factors for MetS were present.

Original language	English
Pages (from-to)	006-011
Number of pages	6
Journal	International Journal of Pharmaceutical Sciences and Developmental Research
Volume	2
Issue number	1
DOIs	https://doi.org/10.17352/ijpsdr.000005
Publication status	Published - 4 Jan 2016

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Copyright the Author(s) 2016. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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10.17352/ijpsdr.000005Licence: CC BY

Publisher version (open access)Final published version, 1.56 MBLicence: CC BY

Cite this

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title = "Antidiabetic, antihypertensive and statin medication use in metabolic syndrome",

abstract = "Background: Metabolic syndrome (MetS) is characterised by a cluster of metabolic risk factors, which eventually increases the risk of diabetes and cardiovascular disease (CVD). The aim of the current study was to investigate medication use in outpatient communities with respect to the occurrence of these metabolic risk factors as defined by ATPIII. Methods: Data for this study was obtained from patients attending a diabetes health screening clinic (DiabHealth) in south-eastern Australia between 2005 and 2011. Participants had a medical history taken and anthropomorphic data collected. Participants with three or more MetS factors were classified as MetS positive as outlined by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Results: Antidiabetic, antihypertensive and antihyperlipidaemic use varies significantly in uptake by participants and with respect to the number of ATPIII factors present. Blood glucose levels (BGL) and the female waist circumference were significantly better in the MetS compared to the non-MetS group. The most increase in medication use in the MetS group was seen for antidiabetic medication (21.3% versus 2.4%, p < 0.01) compared to the non-MetS group. Antihypertensive use tripled (67.8% vs. 26.03%) and Statin use doubled significantly (p<0.01) in the MetS group (21.8% vs. 8.9%). Conclusion: Medication use increases with an increase in ATPIII factors present in the study. Participants with increased BGL (>6.1mmol/L) were not found to have antihyperglycemic medication prescribed. However both antihypertensive medication and Statins were extensively prescribed in cases where only 1 and 2 ATP factors for MetS were present.",

author = "{Ie Butkowski}, E. and L. Brix and Al-Aubaidy, {H. A.} and Hosen Kiat and Jelinek, {H. F.}",

note = "Copyright the Author(s) 2016. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

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doi = "10.17352/ijpsdr.000005",

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AU - Ie Butkowski, E.

AU - Brix, L.

AU - Al-Aubaidy, H. A.

AU - Kiat, Hosen

AU - Jelinek, H. F.

N1 - Copyright the Author(s) 2016. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2016/1/4

Y1 - 2016/1/4

N2 - Background: Metabolic syndrome (MetS) is characterised by a cluster of metabolic risk factors, which eventually increases the risk of diabetes and cardiovascular disease (CVD). The aim of the current study was to investigate medication use in outpatient communities with respect to the occurrence of these metabolic risk factors as defined by ATPIII. Methods: Data for this study was obtained from patients attending a diabetes health screening clinic (DiabHealth) in south-eastern Australia between 2005 and 2011. Participants had a medical history taken and anthropomorphic data collected. Participants with three or more MetS factors were classified as MetS positive as outlined by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Results: Antidiabetic, antihypertensive and antihyperlipidaemic use varies significantly in uptake by participants and with respect to the number of ATPIII factors present. Blood glucose levels (BGL) and the female waist circumference were significantly better in the MetS compared to the non-MetS group. The most increase in medication use in the MetS group was seen for antidiabetic medication (21.3% versus 2.4%, p < 0.01) compared to the non-MetS group. Antihypertensive use tripled (67.8% vs. 26.03%) and Statin use doubled significantly (p<0.01) in the MetS group (21.8% vs. 8.9%). Conclusion: Medication use increases with an increase in ATPIII factors present in the study. Participants with increased BGL (>6.1mmol/L) were not found to have antihyperglycemic medication prescribed. However both antihypertensive medication and Statins were extensively prescribed in cases where only 1 and 2 ATP factors for MetS were present.

AB - Background: Metabolic syndrome (MetS) is characterised by a cluster of metabolic risk factors, which eventually increases the risk of diabetes and cardiovascular disease (CVD). The aim of the current study was to investigate medication use in outpatient communities with respect to the occurrence of these metabolic risk factors as defined by ATPIII. Methods: Data for this study was obtained from patients attending a diabetes health screening clinic (DiabHealth) in south-eastern Australia between 2005 and 2011. Participants had a medical history taken and anthropomorphic data collected. Participants with three or more MetS factors were classified as MetS positive as outlined by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Results: Antidiabetic, antihypertensive and antihyperlipidaemic use varies significantly in uptake by participants and with respect to the number of ATPIII factors present. Blood glucose levels (BGL) and the female waist circumference were significantly better in the MetS compared to the non-MetS group. The most increase in medication use in the MetS group was seen for antidiabetic medication (21.3% versus 2.4%, p < 0.01) compared to the non-MetS group. Antihypertensive use tripled (67.8% vs. 26.03%) and Statin use doubled significantly (p<0.01) in the MetS group (21.8% vs. 8.9%). Conclusion: Medication use increases with an increase in ATPIII factors present in the study. Participants with increased BGL (>6.1mmol/L) were not found to have antihyperglycemic medication prescribed. However both antihypertensive medication and Statins were extensively prescribed in cases where only 1 and 2 ATP factors for MetS were present.

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DO - 10.17352/ijpsdr.000005

M3 - Article

SN - 2640-7760

VL - 2

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EP - 11

JO - International Journal of Pharmaceutical Sciences and Developmental Research

JF - International Journal of Pharmaceutical Sciences and Developmental Research

IS - 1

ER -

Antidiabetic, antihypertensive and statin medication use in metabolic syndrome

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