Antihypertensive drugs and central blood pressure

Carmel M. McEniery*

*Corresponding author for this work

    Research output: Contribution to journalReview article

    11 Citations (Scopus)

    Abstract

    Recent evidence suggests that central blood pressure is a more important determinant of cardiovascular risk than brachial pressure. Interestingly, antihypertensive drugs exert different effects on brachial and central pressure. Traditional β-blockers, such as atenolol, appear to have an adverse impact on central pressure, despite lowering brachial pressure. This may help to explain the results of recent large outcome studies using atenolol. Further research is required to clarify whether other antihypertensive agents lower central pressure beyond the effects observed on brachial pressure.

    Original languageEnglish
    Pages (from-to)253-259
    Number of pages7
    JournalCurrent Hypertension Reports
    Volume11
    Issue number4
    DOIs
    Publication statusPublished - 2009

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