Antihypertensive effect of plasma volume expansion in pregnancy-associated hypertension

E. D.M. Gallery, W. Delprado, A. Z. Gyory

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


Plasma and total extracellular fluid volume expansion was confirmed in normal pregnant women in the third trimester of pregnancy. The plasma volume contraction of pregnancy-associated hypertension (pre-eclampsia) was found to be associated with an increase in the interstitial compartment of extracellular fluid volume. The infusion of a plasma volume expander produced significant amelioration of hypertension for 48 h associated with partial reversal of the disturbance of fluid distribution. This finding confirms the central place of volume contraction in maintenance of elevated blood pressure in pregnancy-associated hypertension.

Original languageEnglish
Pages (from-to)20-24
Number of pages5
JournalAustralian and New Zealand Journal of Medicine
Issue number1
Publication statusPublished - 1981
Externally publishedYes


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