TY - CHAP
T1 - Application of microfluidic technology in cancer research and therapy
AU - Azadi, Shohreh
AU - Aboulkheyr Es, Hamidreza
AU - Kulasinghe, Arutha
AU - Bordhan, Pritam
AU - Ebrahimi Warkiani, Majid
PY - 2020
Y1 - 2020
N2 - Cancer is a heterogeneous disease that requires a multimodal approach to diagnose, manage and treat. A better understanding of the disease biology can lead to identification of novel diagnostic/prognostic biomarkers and the discovery of the novel therapeutics with the goal of improving patient outcomes. Employing advanced technologies can facilitate this, enabling better diagnostic and treatment for cancer patients. In this regard, microfluidic technology has emerged as a promising tool in the studies of cancer, including single cancer cell analysis, modeling angiogenesis and metastasis, drug screening and liquid biopsy. Microfluidic technologies have opened new ways to study tumors in the preclinical and clinical settings. In this chapter, we highlight novel application of this technology in area of fundamental, translational and clinical cancer research.
AB - Cancer is a heterogeneous disease that requires a multimodal approach to diagnose, manage and treat. A better understanding of the disease biology can lead to identification of novel diagnostic/prognostic biomarkers and the discovery of the novel therapeutics with the goal of improving patient outcomes. Employing advanced technologies can facilitate this, enabling better diagnostic and treatment for cancer patients. In this regard, microfluidic technology has emerged as a promising tool in the studies of cancer, including single cancer cell analysis, modeling angiogenesis and metastasis, drug screening and liquid biopsy. Microfluidic technologies have opened new ways to study tumors in the preclinical and clinical settings. In this chapter, we highlight novel application of this technology in area of fundamental, translational and clinical cancer research.
UR - http://www.scopus.com/inward/record.url?scp=85082135791&partnerID=8YFLogxK
U2 - 10.1016/bs.acc.2020.02.012
DO - 10.1016/bs.acc.2020.02.012
M3 - Chapter
C2 - 32951637
AN - SCOPUS:85082135791
SN - 9780128215609
VL - 99
SP - 193
EP - 235
BT - Advances in clinical chemistry
A2 - Makowski, Gregory S.
PB - Academic Press
CY - Cambridge, US ; San Diego, US ; Oxford, UK ; London, UK
ER -