Abstract
Engineered yeast are an important production platform for the biosynthesis of high-value compounds with medical applications. Recent years have witnessed several new developments in this area, largely spurred by advances in the field of synthetic biology and the elucidation of natural metabolic pathways. This minireview presents an overview of synthetic biology applications for the heterologous biosynthesis of biopharmaceuticals in yeast and demonstrates the power and potential of yeast cell factories by highlighting several recent examples. In addition, an outline of emerging trends in this rapidly-developing area is discussed, hinting upon the potential state-of-the-art in the years ahead.
| Original language | English |
|---|---|
| Article number | 340 |
| Pages (from-to) | 1-22 |
| Number of pages | 22 |
| Journal | Genes |
| Volume | 9 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2018 |
Bibliographical note
Copyright the Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.Keywords
- biopharmaceuticals
- biologics
- natural products
- recombinant proteins
- Saccharomy cescerevisiae
- synthetic biology
- yeast