Assay and method for identifying compounds that reduce SIL1 expression or activity

Lars Ittner (Inventor), Janet Van Eersel (Inventor)

Research output: Patent

Abstract

The invention relates to methods and assays for identifying compounds as candidates in the development of a drug for the treatment of various diseases including those associated with pathological Tau. The invention also relates to methods and assays for identifying compounds for the treatment of various diseases including those associated with pathological Tau. The invention also relates to cell lines and constructs for use in an assay of the invention. The methods and assays identify a compound as useful in the treatment of a tauopathy if said compound modulates Sil1 expression or activity.
Original languageEnglish
Patent number10634688
IPCG01N 33/68,C12Q 1/6883
Priority date6/03/13
Filing date6/03/14
Publication statusPublished - 28 Apr 2020

Keywords

  • tau

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