Assessment, monitoring, and management of brain-dead potential organ donors in Australia

Peter S. Macdonald; Anders E M Aneman; Deepak Bhonagiri; Daryl A. Jones; Gerry O'Callaghan; Helen I. Opdam; William Silvester; Geoffrey J. Dobb

doi:10.1007/978-1-4614-4304-9_19

Assessment, monitoring, and management of brain-dead potential organ donors in Australia

Peter S. Macdonald^*, Anders E M Aneman, Deepak Bhonagiri, Daryl A. Jones, Gerry O'Callaghan, Helen I. Opdam, William Silvester, Geoffrey J. Dobb

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Deceased organ donors in Australia are cared for primarily by intensive care specialists and nurses in close consultation with organ and tissue donor coordinators and transplant teams. There has been a substantial increase in the number of deceased multiorgan donors in Australia over the last 4 years. Most of this increase has resulted from increased utilization of DCD (donation after circulatory death) donors and older DBD (donation after brain death) donors. More than 90% of DBD donors are maintained on vasoactive medication after brain death with noradrenaline being the drug of choice in most ICUs. In contrast, the utilization of hormonal therapies either singly or in combination is highly variable across the country. Use of triiodothyronine (T₃) remains controversial. In recent years, T₃ has been administered to 24% of DBD donors, usually in combination with methylprednisolone, vasopressin, and insulin as a combined hormonal protocol for potential cardiothoracic organ donors. Management of the DBD donor in Australia would be facilitated by the development of a nationally uniform evidence-based donor management protocol.

Original language	English
Title of host publication	The brain-dead organ donor
Subtitle of host publication	pathophysiology and management
Editors	Dimitri Novitzky, David K. C. Cooper
Place of Publication	New York
Publisher	Springer, Springer Nature
Pages	237-249
Number of pages	13
ISBN (Electronic)	9781461443049
ISBN (Print)	9781461443032
DOIs	https://doi.org/10.1007/978-1-4614-4304-9_19
Publication status	Published - 1 Mar 2013
Externally published	Yes

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10.1007/978-1-4614-4304-9_19

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Macdonald, P. S., Aneman, A. E. M., Bhonagiri, D., Jones, D. A., O'Callaghan, G., Opdam, H. I., Silvester, W., & Dobb, G. J. (2013). Assessment, monitoring, and management of brain-dead potential organ donors in Australia. In D. Novitzky, & D. K. C. Cooper (Eds.), The brain-dead organ donor: pathophysiology and management (pp. 237-249). Springer, Springer Nature. https://doi.org/10.1007/978-1-4614-4304-9_19

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abstract = "Deceased organ donors in Australia are cared for primarily by intensive care specialists and nurses in close consultation with organ and tissue donor coordinators and transplant teams. There has been a substantial increase in the number of deceased multiorgan donors in Australia over the last 4 years. Most of this increase has resulted from increased utilization of DCD (donation after circulatory death) donors and older DBD (donation after brain death) donors. More than 90% of DBD donors are maintained on vasoactive medication after brain death with noradrenaline being the drug of choice in most ICUs. In contrast, the utilization of hormonal therapies either singly or in combination is highly variable across the country. Use of triiodothyronine (T3) remains controversial. In recent years, T3 has been administered to 24% of DBD donors, usually in combination with methylprednisolone, vasopressin, and insulin as a combined hormonal protocol for potential cardiothoracic organ donors. Management of the DBD donor in Australia would be facilitated by the development of a nationally uniform evidence-based donor management protocol.",

author = "Macdonald, {Peter S.} and Aneman, {Anders E M} and Deepak Bhonagiri and Jones, {Daryl A.} and Gerry O'Callaghan and Opdam, {Helen I.} and William Silvester and Dobb, {Geoffrey J.}",

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Macdonald, PS, Aneman, AEM, Bhonagiri, D, Jones, DA, O'Callaghan, G, Opdam, HI, Silvester, W & Dobb, GJ 2013, Assessment, monitoring, and management of brain-dead potential organ donors in Australia. in D Novitzky & DKC Cooper (eds), The brain-dead organ donor: pathophysiology and management. Springer, Springer Nature, New York, pp. 237-249. https://doi.org/10.1007/978-1-4614-4304-9_19

Assessment, monitoring, and management of brain-dead potential organ donors in Australia. / Macdonald, Peter S.; Aneman, Anders E M; Bhonagiri, Deepak et al.
The brain-dead organ donor: pathophysiology and management. ed. / Dimitri Novitzky; David K. C. Cooper. New York: Springer, Springer Nature, 2013. p. 237-249.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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Assessment, monitoring, and management of brain-dead potential organ donors in Australia

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