TY - JOUR
T1 - Association of hereditary angioedema and hereditary breast cancer
AU - Christie, David R.H.
AU - Kirk, Judy A.
AU - Clarke, Christine L.
AU - Boyages, John
PY - 1997/6
Y1 - 1997/6
N2 - A family is presented in whom hereditary angioedema (HAE) and hereditary breast cancer were coexistent, an association not previously reported. A potential for genetic and treatment-related interactions between the two conditions exists. The use of the hormonal agent danazol to suppress HAE is unlikely to adversely affect the development or outcome of breast cancer. Surgery, chemotheraphy, and radiotherapy were received by affected family members, without triggering edema. Whether hormonal breast cancer treatment affects the suppression of HAE by remains unknown.
AB - A family is presented in whom hereditary angioedema (HAE) and hereditary breast cancer were coexistent, an association not previously reported. A potential for genetic and treatment-related interactions between the two conditions exists. The use of the hormonal agent danazol to suppress HAE is unlikely to adversely affect the development or outcome of breast cancer. Surgery, chemotheraphy, and radiotherapy were received by affected family members, without triggering edema. Whether hormonal breast cancer treatment affects the suppression of HAE by remains unknown.
UR - http://www.scopus.com/inward/record.url?scp=0030927879&partnerID=8YFLogxK
U2 - 10.1016/S0165-4608(96)00218-X
DO - 10.1016/S0165-4608(96)00218-X
M3 - Article
C2 - 9169034
AN - SCOPUS:0030927879
SN - 0165-4608
VL - 95
SP - 159
EP - 162
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 2
ER -